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- W822010902 abstract "Abnormalities of vitamin D metabolism, secondary hyperparathyroidism, acidosis and other less well defined factors are postulated to be important factors in the genesis of altered calcium (Ca) metabolism of chronic renal failure (CRF) and renal osteodystrophy. This study quantitatively characterizes a number of parameters of Ca metabolism in patients with CRF before and after oral administration of pharmacologic quantities of 25* hydroxycholecalciferol (25-OHD3). A previously formulated com-partmental model is used to quantitate certain parameters of Ca metabolism. The model consists of a number of compartments of variable size and intercompartmental transfer rates (1). The experimental data required for this analysis were obtained from a 47Ca tracer kinetic study, a Ca balance study, and the retention of 47Ca in the body as measured by whole body counting techniques. Total body (TB) Ca and phosphorus (P) stores were measured by neutron activation analysis (NAA) and compared to values obtained in normal subjects by methods previously described by this laboratory (2)." @default.
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- W822010902 date "1977-01-01" @default.
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- W822010902 title "Effects of 25-hydroxycholecalciferol on calcium metabolism in chronic renal failure." @default.
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- W822010902 doi "https://doi.org/10.1007/978-1-4613-4217-5_57" @default.
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