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- W82253990 abstract "AIM To evaluate the prevalence of Giardia lamblia infection in patients with irritable bowel syndrome (IBS) and dyspepsia. METHODS We determined G. lamblia antigens in 102 children using enzyme-linked immunosorbent assays (ELISA). We studied the sonographic appearance of the duodenum and colon in giardiasis compared with healthy subjects. RESULTS Giardial lesions of the duodenum and colon were associated with increased wall thickness (p<0.05) and were characterized by increased wall echogenicity, flattening or loss of duodenal folds and/or colonic haustration, hyperechoic floating foci (HFF) demonstrating chaotic motility, increased peri-lesional tissue echogenicity, and altered colonic peristalsis. The prevalence of IBS defined according to Rome criteria was higher in girls (28 vs 17% in boys, p = 0.001). Colonic pain frequency was similar in both genders (14% in girls vs 12% in boys, p = 0.56), however disturbed defecation occurred significantly more often in girls than in boys (19% vs 8%, p = 0.006). Half of the subjects had also dyspeptic symptoms, lactose intolerance and steatorrea. In addition, skin lesions and alopecia were determined in 6% of the patients. CONCLUSION Sonographic features of giardial lesions of the duodenum and colon were distinct from healthy subjects. IBS is common syndrome with the prevalence rates similar to those described in USA. [NIH grant, Russian Federation]." @default.
- W82253990 created "2016-06-24" @default.
- W82253990 creator A5042998191 @default.
- W82253990 date "2009-04-01" @default.
- W82253990 modified "2023-10-14" @default.
- W82253990 title "Giardia‐lamblia infection in hospitalized children with irritable bowel syndrome and dyspepsia: a prospective study" @default.
- W82253990 doi "https://doi.org/10.1096/fasebj.23.1_supplement.980.5" @default.
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