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- W82607486 abstract "This study evaluates the NMR imaging characteristics of stroke and temporal evolution of these features. Patients with acute stroke clinically had NMR imaging (prototype 0.15T resistive imager, Technicare, Inc.) acutely (n=37), at approximately 2 weeks (n=31) and 3 months (n=10). Patients with old (> 1 yr.) stroke were also imaged (n=7). Partial saturation sequences were used employing echo time (T/sub E/) of 30, 60 and 120 msec, as well as inversion recovery (TR) sequences. Partial saturation images displayed a homogeneous increase in signal at lesion sites in both bland and hemorrhagic infarcts, reflection prolongation of spin-spin relaxation (T/sub 2/) due to increased tissue water content, blood and edema being indistinguishable. IR images recovered low signal from bland infarcts due to prolongation of spinlattice relaxation (T/sub 1/) by tissue edema, hemorrhagic lesions and short (T/sub 1/) centrally (blood) with moderate or increased IR signal, and low signal peripherally (edema). On follow-up IR imaging, hematomas developed low signal centres, possibly reflection cavitation, with short T/sub 2/ rims, possibly indicating the presence of iron-laden macrophages. In 2 patients with hemorrhagic infarcts an area of increased signal (prolonged T/sub 2/) was seen on initial partial saturation images in the homologous portion of the othermore » hemisphere (normal by CT). This may reflect a local alteration of blood volume or velocity. In 5 patients with old infarcts, a rim of prolonged T/sub 2/ was seen at the periphery of old lesions, possibly reflecting a local chronic increase in extravascular or intravascular water, slowing of blood velocity, or a zone of neuronal dropout. Detailed pathophysiologic correlation is required to understand the basis of these NMR findings.« less" @default.
- W82607486 created "2016-06-24" @default.
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- W82607486 date "1984-01-01" @default.
- W82607486 modified "2023-09-27" @default.
- W82607486 title "Stroke, evolution of NMR imaging characteristics" @default.
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