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• W82721009 startingPage "355" @default.
• W82721009 abstract "Cell adhesion is an essential prerequisite for survival, communication, and navigation of cells in organisms. It is maintained by the organized binding of molecules from the cell membrane to the extracellular space. This chapter focuses on direct measurements of cellular binding strength at the level of single adhesion molecules. Using atomic force microscopy-based force measurements, adhesion strength can be monitored as a function of adhesion time and environmental conditions. In this way, cellular adhesion strategies like changes in affinity and avidity of adhesion molecules (e.g., integrins) are characterized as well as the molecular arrangement of adhesion molecules in the cell membrane (e.g., molecular clusters, focal adhesion spots, and linkage to the cytoskeleton or tether). Some prominent values for the data evaluation are presented as well as constraints and preparative techniques for successful cell adhesion force experiments." @default.
• W82721009 created "2016-06-24" @default.
• W82721009 creator A5028641883 @default.
• W82721009 creator A5048143369 @default.
• W82721009 date "2011-01-01" @default.
• W82721009 modified "2023-09-27" @default.
• W82721009 title "Measuring Cell Adhesion Forces: Theory and Principles" @default.
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• W82721009 doi "https://doi.org/10.1007/978-1-61779-105-5_21" @default.
• W82721009 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21660737" @default.
• W82721009 hasPublicationYear "2011" @default.
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