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- W827408038 abstract "APPLICATION FIELDS OF CHITOSAN IN TISSUE ENGINEERING ABSTRACT Tissue engineering will provide the most therapeutical strategy of medicine currently and in future. Most of the current investigations concerning regen- erative medicine involves development of supporting and structural materials (scaffold). Chitosan, as a biomaterial, is a focus of interest in tissue engineering by presenting the following features such as being a natural polymer, having a porous structure, being reliable to chemical modifications, easy-to-use in gel form, being biocompatible, and crating non-toxic metabolites. Derivatives of chitin and chitosan are widely used as biomaterials in many fields. Being cell friendly and easy-to-be degraded by lysosomal activity results in its wide us- age in bioengineering. Investigations pointed out its positive effect on tissue growth and tissue layering rates. Possesing a similarity to glycosaminoglycans in tissue matrix, chitosan is defined as a highly suitable biomaterial in connec- tive tissue regenation and organogenesis. In vivo studies represented its ef- fects on increasing number of skin fibroblasts. Membranous form of chitosan has a positive impact on the cellular attachment and penetration. Consider- able mitogenic activity of chitosan in tissue engineering is related to its high degree of deacetylisation. Chitosan, as an organic biomaterial, is strongly preserving its current importance strongly based on its flexibility according to different conditions." @default.
- W827408038 created "2016-06-24" @default.
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- W827408038 date "2010-09-01" @default.
- W827408038 modified "2023-09-23" @default.
- W827408038 title "Doku Mühendisliğinde Kitozanin Kullanim Alanlari" @default.
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