Matches in SemOpenAlex for { <https://semopenalex.org/work/W828347103> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W828347103 endingPage "253" @default.
- W828347103 startingPage "245" @default.
- W828347103 abstract "When it comes to studying the effect of food bioactives on gut health, one of the essential steps that needs to be assessed is characterizing specific effects of the bioactives on the physical barrier of the lumen, the gastrointestinal tissue. In addition to studying the effects on transport function (e.g. by using Ussing chambers or cell culture systems), it is of great interest to evaluate the effects on morphology, cell biology, gene expression, and relevant functions of different cell types that are resident in the gastrointestinal (GI) tract. An ideal near-physiological model should contain a mixture of different GI epithelial cells (e.g. Paneth cells, goblet cells, absorptive and hormone secretive epithelial cells), which can be cultured indefinitely. Recently, the culture and applications of long-term primary multi-cellular cluster structures gastrointestinal organoids (or enteroids) have been demonstrated, and within the last 5 years the number of researchers that commonly use this tissue culture model has increased rapidly. This multi-cellular system may be a promising addition for existing ex vivo and alternative for animal models for testing effects of food bioactives on the intestinal tissue, and could provide a model for pre-screening of compounds prior to moving to the large scale testing systems. Moreover, intestinal organoids can be cultured from different species (e.g. human, pig and mouse). In this chapter we will focus on organoids cultured from mouse and pig crypt cells. We will give a short overview on how to isolate, culture, incubate, and apply them in different research fields." @default.
- W828347103 created "2016-06-24" @default.
- W828347103 creator A5003382998 @default.
- W828347103 creator A5061085648 @default.
- W828347103 date "2015-01-01" @default.
- W828347103 modified "2023-09-23" @default.
- W828347103 title "Intestinal Crypt Organoids as Experimental Models" @default.
- W828347103 cites W111805191 @default.
- W828347103 cites W1965157206 @default.
- W828347103 cites W1982603620 @default.
- W828347103 cites W1996936063 @default.
- W828347103 cites W2002513358 @default.
- W828347103 cites W2003299661 @default.
- W828347103 cites W2031522785 @default.
- W828347103 cites W2043332580 @default.
- W828347103 cites W2055860761 @default.
- W828347103 cites W2080320369 @default.
- W828347103 cites W2086584838 @default.
- W828347103 cites W2104176068 @default.
- W828347103 cites W2110537190 @default.
- W828347103 cites W2116224125 @default.
- W828347103 cites W2143149122 @default.
- W828347103 cites W2152983366 @default.
- W828347103 cites W2157010562 @default.
- W828347103 cites W2329292349 @default.
- W828347103 doi "https://doi.org/10.1007/978-3-319-16104-4_22" @default.
- W828347103 hasPublicationYear "2015" @default.
- W828347103 type Work @default.
- W828347103 sameAs 828347103 @default.
- W828347103 citedByCount "6" @default.
- W828347103 countsByYear W8283471032019 @default.
- W828347103 countsByYear W8283471032021 @default.
- W828347103 countsByYear W8283471032022 @default.
- W828347103 countsByYear W8283471032023 @default.
- W828347103 crossrefType "book-chapter" @default.
- W828347103 hasAuthorship W828347103A5003382998 @default.
- W828347103 hasAuthorship W828347103A5061085648 @default.
- W828347103 hasBestOaLocation W8283471031 @default.
- W828347103 hasConcept C134018914 @default.
- W828347103 hasConcept C150903083 @default.
- W828347103 hasConcept C207001950 @default.
- W828347103 hasConcept C26291073 @default.
- W828347103 hasConcept C2780512811 @default.
- W828347103 hasConcept C2781077229 @default.
- W828347103 hasConcept C31695470 @default.
- W828347103 hasConcept C529295009 @default.
- W828347103 hasConcept C54355233 @default.
- W828347103 hasConcept C55493867 @default.
- W828347103 hasConcept C66090201 @default.
- W828347103 hasConcept C81885089 @default.
- W828347103 hasConcept C86803240 @default.
- W828347103 hasConcept C95444343 @default.
- W828347103 hasConceptScore W828347103C134018914 @default.
- W828347103 hasConceptScore W828347103C150903083 @default.
- W828347103 hasConceptScore W828347103C207001950 @default.
- W828347103 hasConceptScore W828347103C26291073 @default.
- W828347103 hasConceptScore W828347103C2780512811 @default.
- W828347103 hasConceptScore W828347103C2781077229 @default.
- W828347103 hasConceptScore W828347103C31695470 @default.
- W828347103 hasConceptScore W828347103C529295009 @default.
- W828347103 hasConceptScore W828347103C54355233 @default.
- W828347103 hasConceptScore W828347103C55493867 @default.
- W828347103 hasConceptScore W828347103C66090201 @default.
- W828347103 hasConceptScore W828347103C81885089 @default.
- W828347103 hasConceptScore W828347103C86803240 @default.
- W828347103 hasConceptScore W828347103C95444343 @default.
- W828347103 hasLocation W8283471031 @default.
- W828347103 hasOpenAccess W828347103 @default.
- W828347103 hasPrimaryLocation W8283471031 @default.
- W828347103 hasRelatedWork W2036414872 @default.
- W828347103 hasRelatedWork W2272764162 @default.
- W828347103 hasRelatedWork W2419278168 @default.
- W828347103 hasRelatedWork W2435911357 @default.
- W828347103 hasRelatedWork W2800128565 @default.
- W828347103 hasRelatedWork W2915964548 @default.
- W828347103 hasRelatedWork W2966710513 @default.
- W828347103 hasRelatedWork W3147870697 @default.
- W828347103 hasRelatedWork W343823505 @default.
- W828347103 hasRelatedWork W4299413465 @default.
- W828347103 isParatext "false" @default.
- W828347103 isRetracted "false" @default.
- W828347103 magId "828347103" @default.
- W828347103 workType "book-chapter" @default.