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- W8293604 abstract "Behavioral differences between males and females have their origin in brain development. Genetic specification of the gonad leads to secretion of high levels of testosterone in males, which acts on the brain through receptors expressed in subpopulations of cells to influence numbers and types of neurons that mature into adulthood, largely through regulation of programmed cell death. In addition, sex steroid hormones specify sexually dimorphic patterns of connectivity between these cells and other parts of the central nervous system by regulating axon growth and targeting, dendritic morphology, and synaptogenesis. The cell signaling events underlying these developmental processes interact at multiple levels with neurotrophin signal transduction pathways to establish sex-specific patterns of behavior." @default.
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- W8293604 date "2009-01-01" @default.
- W8293604 modified "2023-09-23" @default.
- W8293604 title "Sexual Differentiation of the Central Nervous System" @default.
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- W8293604 doi "https://doi.org/10.1016/b978-008045046-9.01201-8" @default.
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