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- W829685588 abstract "A 43-year-old man was diagnosed with an Eosinophilic fasciitis with cutaneous and articular involvement. The patient experienced an early response with high-dose corticosteroids achieving a global remission of disease. Nevertheless, during the steroids tapering phase, he presented a new flare and subsequently developed a corticosteroid refractory disease. The addition of Methotrexate in monotherapy then associated with an anti-tumor necrosis factor agent did not show any additional benefit. Therefore Tocilizumab, a humanized monoclonal antibody against the interleukin-6 receptor, was initiated achieving an immediate response that persists after 36 months of follow-up. The use of this biological agent allows prednisone withdrawal at 3 months and remission of both articular and cutaneous manifestations at 6 months. This report describes for the first time the efficacy of an anti interleukin-6 agent in Eosinophilic fasciitis treatment." @default.
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- W829685588 date "2015-12-01" @default.
- W829685588 modified "2023-10-16" @default.
- W829685588 title "Efficacy of Tocilizumab in the treatment of Eosinophilic fasciitis: Report of one case" @default.
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- W829685588 doi "https://doi.org/10.1016/j.jbspin.2015.02.008" @default.
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