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• W830294074 abstract "The synthesis of optically active N-propargylindoles has been accomplished via the Cu-catalyzed asymmetric propargylic alkylation of indolines with propargylic esters, followed by the dehydrogenation of the resulting N-substituted indolines with 2,3-dichloro-5,6-dicyano-1,4-benzoquinone. The reaction proceeded in good yield with high enantioselectivity under mild conditions using a bulky and structurally rigid tridentate ketimine P,N,N-ligand, and exhibited a broad substrate scope." @default.
• W830294074 created "2016-06-24" @default.
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• W830294074 creator A5084501389 @default.
• W830294074 date "2015-01-01" @default.
• W830294074 modified "2023-09-26" @default.
• W830294074 title "Enantioselective N-propargylation of indoles via Cu-catalyzed propargylic alkylation/dehydrogenation of indolines" @default.
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• W830294074 doi "https://doi.org/10.1016/s1872-2067(14)60230-8" @default.
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