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• W83049644 abstract "The physical principles of DNA hybridization and folding are described within the context of how they are important for designing optimal PCRs. The multi-state equilibrium model for computing the concentrations of competing unimolecular and bimolecular species is described. Seven PCR design “myths” are stated explicitly, and alternative proper physical models for PCR design are described. This chapter provides both a theoretical framework for understanding PCR design and practical guidelines for users. The Visual-OMP (oligonucleotide modeling platform) package from DNA Software, Inc. is also described." @default.
• W83049644 created "2016-06-24" @default.
• W83049644 creator A5003284540 @default.
• W83049644 date "2007-01-01" @default.
• W83049644 modified "2023-10-10" @default.
• W83049644 title "Physical Principles and Visual-OMP Software for Optimal PCR Design" @default.
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• W83049644 doi "https://doi.org/10.1007/978-1-59745-528-2_1" @default.
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