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- W830751200 abstract "目的：探讨干眼症患者结膜上皮细胞和泪液中肿瘤坏死因子-α（TNF-α）和白细胞介素1β（IL-1β）的表达及临床意义。方法：选择确诊为干眼症患者120例（162眼）和正常人50例（85眼）,采用ELISA法检测泪液中TNF-α、IL-1β的表达,并应用免疫组织化学方法检测结膜上皮细胞中TNF-α、IL-1β的表达。结果：干眼症组患者结膜上皮细胞中TNF-α、IL-1β的阳性表达率均明显高于对照组（P〈0.01）,泪液中TNF-α、IL-1β的表达水平也明显高于对照组（P〈0.01）;干眼症组患者结膜上皮细胞和泪液中TNF-α、IL-1β的表达与BUT、Schii1ner I试验均呈负相关,与角膜荧光素染色呈正相关。结论：TNF-α和IL-1β是干眼症发生的炎性介质,其表达水平变化反映了干眼症的进展过程。" @default.
- W830751200 created "2016-06-24" @default.
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- W830751200 date "2010-01-01" @default.
- W830751200 modified "2023-09-24" @default.
- W830751200 title "干眼症患者结膜上皮细胞和泪液中TNF-α、IL-1β的表达及意义" @default.
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