Matches in SemOpenAlex for { <https://semopenalex.org/work/W83143142> ?p ?o ?g. }
Showing items 1 to 58 of
58
with 100 items per page.
- W83143142 endingPage "20" @default.
- W83143142 startingPage "113" @default.
- W83143142 abstract "An epidemiological study of iodine deficiency disorders covering 4230 pre-adolescent and adolescent school children, together with biochemical analysis of 741 urinary samples, 26 potable drinking water samples and 56 blood samples was conducted in the Plateau State of Nigeria, West Africa. Results indicate that about 2/3 of the region is goitre endemic due principally to iodine deficiency (ID) prevailing in the region as reflected by a low drinking water iodine (DWI) concentrations throughout most of the areas surveyed as well as by a reduced urinary iodide excretions (UIE) seen among the subjects. Urinary thiocyanate (SCN) level in contrast, was found to be significantly higher (P < .01) in the children from these areas as compared to that in Jos (the State capital), raising a possibility of its association with the increased GP seen for the region. Thyroid profile investigation carried out on the 56 goitrous school children from the iodine deficient Bassa region of the state shows two distinct groups. The major group (41 children) exhibited a low-normal to above normal serum T4, FT41 and T4/TBG levels in association with high-normal to above normal serum T3 and a mildly elevated serum TSH activity, suggesting that the group might be in a state of 'compensated euthyroidism'--due as a result of glandular metabolic adaptation to the prevailing ID. The other minor group (15 children) was in 'euthyroid hyperthyroxinaemia' based on a marked rise in serum T4, T3 TBG levels, while serum FT41, T4/TBG ratio and TSH levels were within mid normal range. Discovery of 9 cretins (0.21%) further signifies the magnitude of the problem in the region. It is concluded that a significant proportion of the children living in these areas may likely to suffer from partial thyroid insufficiency with its attendant consequences." @default.
- W83143142 created "2016-06-24" @default.
- W83143142 creator A5030234389 @default.
- W83143142 creator A5042617572 @default.
- W83143142 creator A5064563100 @default.
- W83143142 date "1998-08-26" @default.
- W83143142 modified "2023-09-23" @default.
- W83143142 title "Iodine deficiency disorders in pre-adolescent and adolescent children in Nigeria, West Africa." @default.
- W83143142 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9715118" @default.
- W83143142 hasPublicationYear "1998" @default.
- W83143142 type Work @default.
- W83143142 sameAs 83143142 @default.
- W83143142 citedByCount "2" @default.
- W83143142 crossrefType "journal-article" @default.
- W83143142 hasAuthorship W83143142A5030234389 @default.
- W83143142 hasAuthorship W83143142A5042617572 @default.
- W83143142 hasAuthorship W83143142A5064563100 @default.
- W83143142 hasConcept C126322002 @default.
- W83143142 hasConcept C134018914 @default.
- W83143142 hasConcept C191897082 @default.
- W83143142 hasConcept C192562407 @default.
- W83143142 hasConcept C2776600448 @default.
- W83143142 hasConcept C2777195454 @default.
- W83143142 hasConcept C2778660577 @default.
- W83143142 hasConcept C526584372 @default.
- W83143142 hasConcept C539932907 @default.
- W83143142 hasConcept C71924100 @default.
- W83143142 hasConceptScore W83143142C126322002 @default.
- W83143142 hasConceptScore W83143142C134018914 @default.
- W83143142 hasConceptScore W83143142C191897082 @default.
- W83143142 hasConceptScore W83143142C192562407 @default.
- W83143142 hasConceptScore W83143142C2776600448 @default.
- W83143142 hasConceptScore W83143142C2777195454 @default.
- W83143142 hasConceptScore W83143142C2778660577 @default.
- W83143142 hasConceptScore W83143142C526584372 @default.
- W83143142 hasConceptScore W83143142C539932907 @default.
- W83143142 hasConceptScore W83143142C71924100 @default.
- W83143142 hasIssue "2" @default.
- W83143142 hasLocation W831431421 @default.
- W83143142 hasOpenAccess W83143142 @default.
- W83143142 hasPrimaryLocation W831431421 @default.
- W83143142 hasRelatedWork W1968910484 @default.
- W83143142 hasRelatedWork W1984618852 @default.
- W83143142 hasRelatedWork W2006971532 @default.
- W83143142 hasRelatedWork W2011761361 @default.
- W83143142 hasRelatedWork W2011960454 @default.
- W83143142 hasRelatedWork W2072722788 @default.
- W83143142 hasRelatedWork W2079221060 @default.
- W83143142 hasRelatedWork W2114465010 @default.
- W83143142 hasRelatedWork W2405445270 @default.
- W83143142 hasRelatedWork W2009143186 @default.
- W83143142 hasVolume "17" @default.
- W83143142 isParatext "false" @default.
- W83143142 isRetracted "false" @default.
- W83143142 magId "83143142" @default.
- W83143142 workType "article" @default.