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• W83205846 abstract "Event Abstract Back to Event Feeding pattern after intraperitoneal capsaicin desensitization in rats Peter Cseplo1, Andras Garami1, Margit Solymár1, Marta Balasko1, Erika Petervari1 and Miklos Szekely1* 1 University of Pecs, Department of Pathophysiology and Gerontology, Hungary In regulation of satiety and hunger, similarly as in the regulation of postprandial hypermetabolism or fasting hypometabolism there may be a role for neural information from the abdominal cavity. Capsaicin-sensitive afferent abdominal vagal fibers may influence both onset and cessation of feeding, i.e. the feeding pattern, besides influencing the total amount of food consumed. In the present experiments strictly the local (abdominal) afferent fibers were desensitized by intraperitoneal (IP) application of small dose capsaicin. For this purpose, 4-months-old male Wistar rats were injected IP with 2+3 mg/kg capsaicin a few days after IP implantation of telemetric sensors of body temperature, heart rate and spontaneous activity. The animals were placed into the biotelemetric system to record these signals along with feeding frequency (FF) and feeding duration (FD) registered by the infrared Feeding monitor. The amount of consumed food was measured manually. One week after the desensitization a 5-days-long fasting followed to check the usually defective hypometabolic adaptation to fasting in desensitized animals (enhanced tendency for hyperthermic periods), then the food was returned and FD, FF and the food consumption were analyzed. During the first hour of re-feeding, the desensitized rats ate significantly more than the controls and the difference was sustained for well over 3 hours. As expected, in desensitized rats the FD was longer in some fractions of the first hour, but FF was also higher. Besides, the elevation of these parameters was more prolonged. Apparently, IP neural signals influence feeding behavior. Support: OTKA 49321 Conference: 12th Meeting of the Hungarian Neuroscience Society, Budapest, Hungary, 22 Jan - 24 Jan, 2009. Presentation Type: Poster Presentation Topic: Homeostatic regulatory mechanisms Citation: Cseplo P, Garami A, Solymár M, Balasko M, Petervari E and Szekely M (2009). Feeding pattern after intraperitoneal capsaicin desensitization in rats. Front. Syst. Neurosci. Conference Abstract: 12th Meeting of the Hungarian Neuroscience Society. doi: 10.3389/conf.neuro.01.2009.04.006 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 02 Mar 2009; Published Online: 02 Mar 2009. * Correspondence: Miklos Szekely, University of Pecs, Department of Pathophysiology and Gerontology, Pecs, Hungary, miklos.szekely@aok.pte.hu Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Peter Cseplo Andras Garami Margit Solymár Marta Balasko Erika Petervari Miklos Szekely Google Peter Cseplo Andras Garami Margit Solymár Marta Balasko Erika Petervari Miklos Szekely Google Scholar Peter Cseplo Andras Garami Margit Solymár Marta Balasko Erika Petervari Miklos Szekely PubMed Peter Cseplo Andras Garami Margit Solymár Marta Balasko Erika Petervari Miklos Szekely Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page." @default.
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• W83205846 title "Feeding pattern after intraperitoneal capsaicin desensitization in rats" @default.
• W83205846 doi "https://doi.org/10.3389/conf.neuro.01.2009.04.006" @default.
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