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- W83408091 abstract "Reactive oxygen species occur in tissues and can damage DNA, proteins, carbohydrates, and lipids. These potentially deleterious reactions are controlled by a system of enzymatic and nonenzymatic antioxidants which eliminate pro-oxidants and scavenge free radicals. Tocopherols are the most abundant and efficient scavengers of hydroxyl radicals in biological membranes. Water-soluble antioxidants include ascorbate and cellular thiols. The ability of lipid-soluble carotenoids to quench singlet molecular oxygen may explain anticancer properties of the carotenoids, independent of their provitamin A activity. Glutathione is an important substrate for enzymatic antioxidant functions and is capable of nonenzymatic radical scavenging. Thiols associated with membrane proteins may also be important to the antioxidant system. Interactions between the thiols, tocopherols, and other compounds enhance the effectiveness of cellular antioxidative defense." @default.
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- W83408091 date "1992-01-01" @default.
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- W83408091 title "Tocopherols, Carotenoids and The Glutathione System" @default.
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