FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W836498138> ?p ?o ?g. }

• W836498138 endingPage "e0130190" @default.
• W836498138 startingPage "e0130190" @default.
• W836498138 abstract "The use of solar irradiation to sterilize water prior to its consumption has resulted in the reduction of water related illnesses in waterborne disease endemic communities worldwide. Currently, research on solar water disinfection (SODIS) has been directed towards understanding the underlying mechanisms through which solar irradiation inactivates the culturability of microorganisms in water, enhancement of the disinfection process, and the health impact of SODIS water consumption. However, the immunological consequences of SODIS water consumption have not been explored. In this study, we investigated the effect that solar irradiated V. cholerae may have had on the secretion of cytokines and chemokines by the JAWS II dendritic cell line in vitro. The JAWS II dendritic cell line was stimulated with the different strains of V. cholerae that had been: (i) prepared in PBS, (ii) inactivated through a combination of heat and chemical, (iii) solar irradiated, and (iv) non-solar irradiated, in bottled water. As controls, LPS (1 μg/ml) and CTB (1 μg/ml) were used as stimulants. After 48 hours of stimulation the tissue culture media from each treatment was qualitatively and quantitatively analysed for the presence of IL-1α, IL-1β, IL-6, IL-7, IL-10, IL-12p40, IL-12p70, IL-15, MIP-1α, MIP-1β, MIP-2, RANTES, TNF-α, IL-23 and IL-27. Results showed that solar irradiated cultures of V. cholerae induced dendritic cells to secrete significant (p<0.05) levels of pro-inflammatory cytokines in comparison to the unstimulated dendritic cells. Furthermore, the amount of pro-inflammatory cytokines secreted by the dendritic cells in response to solar irradiated cultures of V. cholerae was not as high as observed in treatments involving non-solar irradiated cultures of V. cholerae or LPS. Our results suggest that solar irradiated microorganisms are capable of inducing the secretion of pro-inflammatory cytokines and chemokines. This novel finding is key towards understanding the possible immunological consequences of consuming SODIS treated water." @default.
• W836498138 created "2016-06-24" @default.
• W836498138 creator A5021377995 @default.
• W836498138 creator A5030044199 @default.
• W836498138 creator A5041278181 @default.
• W836498138 creator A5066267773 @default.
• W836498138 date "2015-06-11" @default.
• W836498138 modified "2023-09-26" @default.
• W836498138 title "The Effect of Solar Irradiated Vibrio cholerae on the Secretion of Pro-Inflammatory Cytokines and Chemokines by the JAWS II Dendritic Cell Line In Vitro" @default.
• W836498138 cites W1484873793 @default.
• W836498138 cites W1497555487 @default.
• W836498138 cites W1520336798 @default.
• W836498138 cites W1533878687 @default.
• W836498138 cites W1549430246 @default.
• W836498138 cites W1573605572 @default.
• W836498138 cites W1594774706 @default.
• W836498138 cites W1869598868 @default.
• W836498138 cites W1934903117 @default.
• W836498138 cites W1971653058 @default.
• W836498138 cites W1979535340 @default.
• W836498138 cites W1980511941 @default.
• W836498138 cites W1980640110 @default.
• W836498138 cites W1981603866 @default.
• W836498138 cites W1985892309 @default.
• W836498138 cites W1993244275 @default.
• W836498138 cites W1996432214 @default.
• W836498138 cites W1998480304 @default.
• W836498138 cites W2010358244 @default.
• W836498138 cites W2022292514 @default.
• W836498138 cites W2033058796 @default.
• W836498138 cites W2033507649 @default.
• W836498138 cites W2036494515 @default.
• W836498138 cites W2037357452 @default.
• W836498138 cites W2047204509 @default.
• W836498138 cites W2047544732 @default.
• W836498138 cites W2048216527 @default.
• W836498138 cites W2063120338 @default.
• W836498138 cites W2069968649 @default.
• W836498138 cites W2079449263 @default.
• W836498138 cites W2083360217 @default.
• W836498138 cites W2101992616 @default.
• W836498138 cites W2105459119 @default.
• W836498138 cites W2107050201 @default.
• W836498138 cites W2111195194 @default.
• W836498138 cites W2111749427 @default.
• W836498138 cites W2112161630 @default.
• W836498138 cites W2115066482 @default.
• W836498138 cites W2118837440 @default.
• W836498138 cites W2124707045 @default.
• W836498138 cites W2128519954 @default.
• W836498138 cites W2135389813 @default.
• W836498138 cites W2142071856 @default.
• W836498138 cites W2149503929 @default.
• W836498138 cites W2153362879 @default.
• W836498138 cites W2155622962 @default.
• W836498138 cites W2156201144 @default.
• W836498138 cites W2157307003 @default.
• W836498138 cites W2167795546 @default.
• W836498138 cites W2414842942 @default.
• W836498138 cites W3023923910 @default.
• W836498138 doi "https://doi.org/10.1371/journal.pone.0130190" @default.
• W836498138 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4465907" @default.
• W836498138 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26066787" @default.
• W836498138 hasPublicationYear "2015" @default.
• W836498138 type Work @default.
• W836498138 sameAs 836498138 @default.
• W836498138 citedByCount "5" @default.
• W836498138 countsByYear W8364981382017 @default.
• W836498138 countsByYear W8364981382021 @default.
• W836498138 countsByYear W8364981382022 @default.
• W836498138 crossrefType "journal-article" @default.
• W836498138 hasAuthorship W836498138A5021377995 @default.
• W836498138 hasAuthorship W836498138A5030044199 @default.
• W836498138 hasAuthorship W836498138A5041278181 @default.
• W836498138 hasAuthorship W836498138A5066267773 @default.
• W836498138 hasBestOaLocation W8364981381 @default.
• W836498138 hasConcept C13373296 @default.
• W836498138 hasConcept C164027704 @default.
• W836498138 hasConcept C185592680 @default.
• W836498138 hasConcept C203014093 @default.
• W836498138 hasConcept C2776914184 @default.
• W836498138 hasConcept C2778170410 @default.
• W836498138 hasConcept C2778643871 @default.
• W836498138 hasConcept C2778690821 @default.
• W836498138 hasConcept C49039625 @default.
• W836498138 hasConcept C523546767 @default.
• W836498138 hasConcept C54355233 @default.
• W836498138 hasConcept C55493867 @default.
• W836498138 hasConcept C81885089 @default.
• W836498138 hasConcept C86803240 @default.
• W836498138 hasConcept C8891405 @default.
• W836498138 hasConcept C89423630 @default.
• W836498138 hasConceptScore W836498138C13373296 @default.
• W836498138 hasConceptScore W836498138C164027704 @default.
• W836498138 hasConceptScore W836498138C185592680 @default.
• W836498138 hasConceptScore W836498138C203014093 @default.
• W836498138 hasConceptScore W836498138C2776914184 @default.
• W836498138 hasConceptScore W836498138C2778170410 @default.

• next