Matches in SemOpenAlex for { <https://semopenalex.org/work/W836840087> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W836840087 startingPage "3566" @default.
- W836840087 abstract "Background: It is necessary to categorize subpopulations of COPD or smokers by non-outcome phenotypes, such as emphysema without airflow obstruction.Methods: 730 current- or ex-smokers including 382 COPD subjects were studied (66.7±11.0 yrs, 602male/128 females). We collected the data for all the subjects on pulmonary function test, 6 minute walking test (6MWT), body mass index (BMI), dysnpea (modified Medical Research Council (MMRC) Dyspnea Scale, Oxygen Cost Diagram (OCD)), and the extent of emphysema and airway disease assessed by chest computed tomography (CT) (low attenuation area (LAA)% and wall area (WA)%), and we also studied the data on the score of St. George's Respiratory Questionnaire (SGRQ) for QOL [n = 361], and exacerbations [n = 178]. We performed a principal component analysis (PCA) and cluster analysis by k-means method.Results: PCA showed the major factors as follows: vital capacity (VC), LAA%, WA%, reversibility, PaO2, PaCO2, leg fatigue on 6MWT.Cluster analysis with these factors classified the subjects into four clusters as follows: Cluster 1; 254 cases with mild emphysema (LAA% 22.1±10.8, WA% 45.0±14.1), Cluster 2; 156 cases with airway disease (LAA% 15.7±11.3, WA% 58.3±12.8), Cluster 3; 152 cases with emphysema and airway disease (LAA% 20.1±13.2, WA% 61.5±11.5), Cluster 4; 168 cases with severe emphysema (LAA% 41.0±11.8, WA% 57.0±11.3).Cluster 4 has the highest SGRQ score (p < 0.0001). Cluster 2 and 4 were more prone to exacerbations (p < 0.01).Conclusions: PCA and cluster analysis revealed that chest CT contributes to the classification to subpopulations in smoker with or without COPD." @default.
- W836840087 created "2016-06-24" @default.
- W836840087 creator A5011533142 @default.
- W836840087 creator A5016020165 @default.
- W836840087 creator A5018067940 @default.
- W836840087 creator A5018362000 @default.
- W836840087 creator A5024996463 @default.
- W836840087 creator A5036084648 @default.
- W836840087 creator A5037856759 @default.
- W836840087 creator A5053138435 @default.
- W836840087 creator A5060449395 @default.
- W836840087 creator A5067052172 @default.
- W836840087 date "2011-09-01" @default.
- W836840087 modified "2023-09-26" @default.
- W836840087 title "Cluster analysis revealed differences on quality of life and susceptibility to exacerbation between subpopulations of smokers including COPD" @default.
- W836840087 hasPublicationYear "2011" @default.
- W836840087 type Work @default.
- W836840087 sameAs 836840087 @default.
- W836840087 citedByCount "0" @default.
- W836840087 crossrefType "journal-article" @default.
- W836840087 hasAuthorship W836840087A5011533142 @default.
- W836840087 hasAuthorship W836840087A5016020165 @default.
- W836840087 hasAuthorship W836840087A5018067940 @default.
- W836840087 hasAuthorship W836840087A5018362000 @default.
- W836840087 hasAuthorship W836840087A5024996463 @default.
- W836840087 hasAuthorship W836840087A5036084648 @default.
- W836840087 hasAuthorship W836840087A5037856759 @default.
- W836840087 hasAuthorship W836840087A5053138435 @default.
- W836840087 hasAuthorship W836840087A5060449395 @default.
- W836840087 hasAuthorship W836840087A5067052172 @default.
- W836840087 hasConcept C105922876 @default.
- W836840087 hasConcept C126322002 @default.
- W836840087 hasConcept C159110408 @default.
- W836840087 hasConcept C164705383 @default.
- W836840087 hasConcept C164866538 @default.
- W836840087 hasConcept C1862650 @default.
- W836840087 hasConcept C199360897 @default.
- W836840087 hasConcept C2776780178 @default.
- W836840087 hasConcept C2777014857 @default.
- W836840087 hasConcept C2778333281 @default.
- W836840087 hasConcept C2779951463 @default.
- W836840087 hasConcept C2780221984 @default.
- W836840087 hasConcept C41008148 @default.
- W836840087 hasConcept C42219234 @default.
- W836840087 hasConcept C534529494 @default.
- W836840087 hasConcept C71924100 @default.
- W836840087 hasConcept C75603125 @default.
- W836840087 hasConceptScore W836840087C105922876 @default.
- W836840087 hasConceptScore W836840087C126322002 @default.
- W836840087 hasConceptScore W836840087C159110408 @default.
- W836840087 hasConceptScore W836840087C164705383 @default.
- W836840087 hasConceptScore W836840087C164866538 @default.
- W836840087 hasConceptScore W836840087C1862650 @default.
- W836840087 hasConceptScore W836840087C199360897 @default.
- W836840087 hasConceptScore W836840087C2776780178 @default.
- W836840087 hasConceptScore W836840087C2777014857 @default.
- W836840087 hasConceptScore W836840087C2778333281 @default.
- W836840087 hasConceptScore W836840087C2779951463 @default.
- W836840087 hasConceptScore W836840087C2780221984 @default.
- W836840087 hasConceptScore W836840087C41008148 @default.
- W836840087 hasConceptScore W836840087C42219234 @default.
- W836840087 hasConceptScore W836840087C534529494 @default.
- W836840087 hasConceptScore W836840087C71924100 @default.
- W836840087 hasConceptScore W836840087C75603125 @default.
- W836840087 hasLocation W8368400871 @default.
- W836840087 hasOpenAccess W836840087 @default.
- W836840087 hasPrimaryLocation W8368400871 @default.
- W836840087 hasRelatedWork W1860413778 @default.
- W836840087 hasRelatedWork W1873475237 @default.
- W836840087 hasRelatedWork W2060660717 @default.
- W836840087 hasRelatedWork W2127822908 @default.
- W836840087 hasRelatedWork W2167070869 @default.
- W836840087 hasRelatedWork W2244208562 @default.
- W836840087 hasRelatedWork W2380473096 @default.
- W836840087 hasRelatedWork W2510917076 @default.
- W836840087 hasRelatedWork W2736642796 @default.
- W836840087 hasRelatedWork W2762686188 @default.
- W836840087 hasRelatedWork W2772341796 @default.
- W836840087 hasRelatedWork W2779021798 @default.
- W836840087 hasRelatedWork W2780097029 @default.
- W836840087 hasRelatedWork W2898063749 @default.
- W836840087 hasRelatedWork W2955978118 @default.
- W836840087 hasRelatedWork W3032844676 @default.
- W836840087 hasRelatedWork W3044093580 @default.
- W836840087 hasRelatedWork W3096977422 @default.
- W836840087 hasRelatedWork W1944840183 @default.
- W836840087 hasRelatedWork W2518170291 @default.
- W836840087 hasVolume "38" @default.
- W836840087 isParatext "false" @default.
- W836840087 isRetracted "false" @default.
- W836840087 magId "836840087" @default.
- W836840087 workType "article" @default.