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- W837843062 abstract "After rats were deprived of water for 21-1/2 hours, one of the following 14 treatments was given to each subject: intraperitoneal injection of 2,4,6, or 8 cc of water, 2, 4, 6, or 8 cc of 0.45 per cent NaCl solution, or 2, 4, 6, or 8 cc of 0.9 per cent, NaCl solution; or one of two control conditions which consisted of sham injection or a 30-minute period with free access to water. Thirty minutes following the treatment either food or water was presented for one hour to assess the effects of the treatment. This period was followed by a one-hour recovery period during which both food and water were provided. The results indicated that injection of isotonic saline failed to either reduce water intake or increase food intake beyond the sham control level, but injections of distilled water and hypotonic saline altered water and food intake in proportion to the amount injected. Overall, injection of 0.45 per cent saline was half as effective as water injec tion on both food and water intake. The complex thirst induced by water deprivation was not reduced by extracellular volume restoration. The conclusion was reached that intracellular hydration is necessary to reduce the complex thirst which subsequently induces appetite for food." @default.
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- W837843062 date "1969-01-01" @default.
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- W837843062 title "Effect of restoration of body fluid on food and water intake in water deprived rats" @default.
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