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• W83802967 abstract "A bacterial biodetection system has been developed for rapid detection of environmental genotoxins. This cellular bioassay is based on the receptor reporter principle with the SOS system as receptor sensitive to DNA damage and the biolu­ minescence system as rapid optical reporter. Since the bioassay combines the SOS system with the bioluminescence system, we have termed it sos lux test. For the SOS lux test, a recombinant plasmid pPLSI (DSM 10333) was constructed in which the promoterless operon of bioluminescence of Photo bacterium leiognathi 54DI0 (lux C,D,A,B,F,E) (Krasnojarsk Institute of Biophysics Collection) is under control of a SOS promoter (part of the cda gene of the plasmid ColD, which carries a strong SOS promoter). This plasmid pPLSI can be used to transform any Escherichia coli recA+ system or other microorganisms with a SOS system, suitable for the detection of a" @default.
• W83802967 created "2016-06-24" @default.
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• W83802967 date "1998-01-01" @default.
• W83802967 modified "2023-09-23" @default.
• W83802967 title "Monitoring of Genotoxicity, 5.1 Recombinant Escherichia Coli Cells as Biodetector System for Genotoxins" @default.
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• W83802967 hasPublicationYear "1998" @default.
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