FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W8381561> ?p ?o ?g. }

• W8381561 endingPage "4" @default.
• W8381561 startingPage "2772" @default.
• W8381561 abstract "To investigate the existence of a water channel in the frog corneal epithelium by studying the osmotic water permeability (Pf) of Xenopus oocytes expressing the mRNA message from frog corneal epithelium.Total RNA was obtained from corneal epithelium by a single-step phase separation method, and poly A+ RNA was isolated using oligo-dT columns. This mRNA was injected into the oocytes. After a 48-hour incubation, oocyte volume changes elicited by a hypoosmotic solution were measured with a computerized video system.Oocytes injected with 50 nl mRNA (1 microgram/microliter) showed a significant increase in Pf compared to water-injected controls (8.4 +/- 1.5 to 17.5 +/- 1.9 cm.sec-1 x 10(-4), P < 0.005). mRNA-injected oocytes exposed to a higher external [Cl-] showed a heightened permeability. Furthermore, Pf of oocytes exposed to a solution containing the recognized water-channel blocker HgCl2 was significantly lower than the Pf of mRNA-injected oocytes not exposed to HgCl2.Evidence was found for a water channel in the frog corneal epithelium because oocytes injected with the epithelial mRNA manifested increased water permeability. The increase in water permeability was larger in the presence of external Cl- and was inhibited by HgCl2. This finding correlates with measurements of Pf in the intact epithelium in which apical Cl- induced an increase in transepithelial water permeability prevented by HgCl2." @default.
• W8381561 created "2016-06-24" @default.
• W8381561 creator A5002188014 @default.
• W8381561 creator A5026067574 @default.
• W8381561 creator A5047162713 @default.
• W8381561 creator A5057436850 @default.
• W8381561 creator A5070049744 @default.
• W8381561 creator A5070852297 @default.
• W8381561 date "1995-12-01" @default.
• W8381561 modified "2023-09-23" @default.
• W8381561 title "mRNA from frog corneal epithelium increases water permeability in Xenopus oocytes." @default.
• W8381561 cites W1501416370 @default.
• W8381561 cites W2007614459 @default.
• W8381561 cites W2042279757 @default.
• W8381561 cites W2052922251 @default.
• W8381561 cites W2055278115 @default.
• W8381561 cites W2072251236 @default.
• W8381561 cites W2078026645 @default.
• W8381561 cites W2090144945 @default.
• W8381561 cites W2093407677 @default.
• W8381561 cites W2160118062 @default.
• W8381561 cites W2409287839 @default.
• W8381561 cites W83841204 @default.
• W8381561 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7499101" @default.
• W8381561 hasPublicationYear "1995" @default.
• W8381561 type Work @default.
• W8381561 sameAs 8381561 @default.
• W8381561 citedByCount "3" @default.
• W8381561 countsByYear W83815612016 @default.
• W8381561 crossrefType "journal-article" @default.
• W8381561 hasAuthorship W8381561A5002188014 @default.
• W8381561 hasAuthorship W8381561A5026067574 @default.
• W8381561 hasAuthorship W8381561A5047162713 @default.
• W8381561 hasAuthorship W8381561A5057436850 @default.
• W8381561 hasAuthorship W8381561A5070049744 @default.
• W8381561 hasAuthorship W8381561A5070852297 @default.
• W8381561 hasConcept C104317684 @default.
• W8381561 hasConcept C105580179 @default.
• W8381561 hasConcept C105702510 @default.
• W8381561 hasConcept C120882062 @default.
• W8381561 hasConcept C12554922 @default.
• W8381561 hasConcept C126322002 @default.
• W8381561 hasConcept C134018914 @default.
• W8381561 hasConcept C153911025 @default.
• W8381561 hasConcept C16685009 @default.
• W8381561 hasConcept C176704843 @default.
• W8381561 hasConcept C185592680 @default.
• W8381561 hasConcept C196843134 @default.
• W8381561 hasConcept C2776690073 @default.
• W8381561 hasConcept C2778935311 @default.
• W8381561 hasConcept C2779257441 @default.
• W8381561 hasConcept C2779535977 @default.
• W8381561 hasConcept C41625074 @default.
• W8381561 hasConcept C529295009 @default.
• W8381561 hasConcept C54355233 @default.
• W8381561 hasConcept C55493867 @default.
• W8381561 hasConcept C71924100 @default.
• W8381561 hasConcept C86803240 @default.
• W8381561 hasConcept C95444343 @default.
• W8381561 hasConceptScore W8381561C104317684 @default.
• W8381561 hasConceptScore W8381561C105580179 @default.
• W8381561 hasConceptScore W8381561C105702510 @default.
• W8381561 hasConceptScore W8381561C120882062 @default.
• W8381561 hasConceptScore W8381561C12554922 @default.
• W8381561 hasConceptScore W8381561C126322002 @default.
• W8381561 hasConceptScore W8381561C134018914 @default.
• W8381561 hasConceptScore W8381561C153911025 @default.
• W8381561 hasConceptScore W8381561C16685009 @default.
• W8381561 hasConceptScore W8381561C176704843 @default.
• W8381561 hasConceptScore W8381561C185592680 @default.
• W8381561 hasConceptScore W8381561C196843134 @default.
• W8381561 hasConceptScore W8381561C2776690073 @default.
• W8381561 hasConceptScore W8381561C2778935311 @default.
• W8381561 hasConceptScore W8381561C2779257441 @default.
• W8381561 hasConceptScore W8381561C2779535977 @default.
• W8381561 hasConceptScore W8381561C41625074 @default.
• W8381561 hasConceptScore W8381561C529295009 @default.
• W8381561 hasConceptScore W8381561C54355233 @default.
• W8381561 hasConceptScore W8381561C55493867 @default.
• W8381561 hasConceptScore W8381561C71924100 @default.
• W8381561 hasConceptScore W8381561C86803240 @default.
• W8381561 hasConceptScore W8381561C95444343 @default.
• W8381561 hasIssue "13" @default.
• W8381561 hasLocation W83815611 @default.
• W8381561 hasOpenAccess W8381561 @default.
• W8381561 hasPrimaryLocation W83815611 @default.
• W8381561 hasRelatedWork W2012680209 @default.
• W8381561 hasRelatedWork W2028474692 @default.
• W8381561 hasRelatedWork W2037200938 @default.
• W8381561 hasRelatedWork W2048574507 @default.
• W8381561 hasRelatedWork W2077909456 @default.
• W8381561 hasRelatedWork W2101118515 @default.
• W8381561 hasRelatedWork W2152903957 @default.
• W8381561 hasRelatedWork W2167846336 @default.
• W8381561 hasRelatedWork W2329351727 @default.
• W8381561 hasRelatedWork W8381561 @default.
• W8381561 hasVolume "36" @default.
• W8381561 isParatext "false" @default.

• next