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• W843380119 abstract "This dissertation is composed of five major chapters. The first is a review of the literature discussing the secreted growth factor Wnt11 with particular interest in the Wnt11dependent signaling cascades that regulate cell movements, followed by three chapters of research findings, and a final concluding chapter. Wnts are encoded by a family of 19 genes that play roles in development and disease. Homologs of Wnt11 are important regulators of cell movements in gastrulating embryos. In addition to gastrulation, Wnt11 genes show expression in other embryonic tissue including neural crest cells, the heart and the somite. Following the literature review, the first three chapters describe research that studies the roles of Wnt11-signaling during the development of the heart and neural crest. The first one demonstrates that Wnt11-signaling is required for heart morphogenesis. This work also refutes a proposed role for Wnt11 as a heart inducer. Next, the role of Wnt11 homologs is studied in the regulation of cranial and trunk neural crest cell migration. During neural crest development two Wnt genes are redundantly required to regulate cell migration Wnt11 and Wnt11-related (Wnt11-R). Trunk neural crest migration requires Wnt11-R for migration into the dorsal fin. Alternatively, cranial neural crest development predominantly requires Wnt11 while more severe migratory defects are observed when Wnt11 and Wnt11-R are co-inhibited. A final chapter discusses the overall conclusions about the general role that Wnt11 genes play during embryonic development." @default.
• W843380119 created "2016-06-24" @default.
• W843380119 creator A5076411441 @default.
• W843380119 date "2006-01-01" @default.
• W843380119 modified "2023-09-24" @default.
• W843380119 title "Wnt11-Signaling Regulates Cardiac and Neural Crest Development" @default.
• W843380119 cites W110331459 @default.
• W843380119 cites W128720583 @default.
• W843380119 cites W1485377536 @default.
• W843380119 cites W1504655784 @default.
• W843380119 cites W154439523 @default.
• W843380119 cites W1559850800 @default.
• W843380119 cites W1564357553 @default.
• W843380119 cites W1571217264 @default.
• W843380119 cites W15778579 @default.
• W843380119 cites W1760771044 @default.
• W843380119 cites W1867413792 @default.
• W843380119 cites W1899017196 @default.
• W843380119 cites W1904089240 @default.
• W843380119 cites W1926045309 @default.
• W843380119 cites W1931761759 @default.
• W843380119 cites W1936195691 @default.
• W843380119 cites W1945116336 @default.
• W843380119 cites W1964147560 @default.
• W843380119 cites W1964743891 @default.
• W843380119 cites W1965927965 @default.
• W843380119 cites W1967195690 @default.
• W843380119 cites W1971221092 @default.
• W843380119 cites W1971806121 @default.
• W843380119 cites W1974596653 @default.
• W843380119 cites W1974712344 @default.
• W843380119 cites W1975681150 @default.
• W843380119 cites W1975853332 @default.
• W843380119 cites W1978047924 @default.
• W843380119 cites W1978379357 @default.
• W843380119 cites W1986210731 @default.
• W843380119 cites W1989721036 @default.
• W843380119 cites W1989918771 @default.
• W843380119 cites W1990296255 @default.
• W843380119 cites W1990976157 @default.
• W843380119 cites W1991461487 @default.
• W843380119 cites W1991738093 @default.
• W843380119 cites W1993199560 @default.
• W843380119 cites W1995238865 @default.
• W843380119 cites W1997368786 @default.
• W843380119 cites W1999912060 @default.
• W843380119 cites W2000476522 @default.
• W843380119 cites W2000839363 @default.
• W843380119 cites W2001856716 @default.
• W843380119 cites W2004426310 @default.
• W843380119 cites W2006417453 @default.
• W843380119 cites W2006428917 @default.
• W843380119 cites W2006671195 @default.
• W843380119 cites W2007421374 @default.
• W843380119 cites W2007675427 @default.
• W843380119 cites W2007817359 @default.
• W843380119 cites W2011315338 @default.
• W843380119 cites W2012725470 @default.
• W843380119 cites W2013548303 @default.
• W843380119 cites W2016836965 @default.
• W843380119 cites W2017668082 @default.
• W843380119 cites W2022798578 @default.
• W843380119 cites W2023099007 @default.
• W843380119 cites W2027255572 @default.
• W843380119 cites W2027356109 @default.
• W843380119 cites W2029142481 @default.
• W843380119 cites W2029529421 @default.
• W843380119 cites W2029634472 @default.
• W843380119 cites W2030491643 @default.
• W843380119 cites W2031112866 @default.
• W843380119 cites W2031450930 @default.
• W843380119 cites W2033984390 @default.
• W843380119 cites W2034351801 @default.
• W843380119 cites W2045562694 @default.
• W843380119 cites W2046248524 @default.
• W843380119 cites W2046949570 @default.
• W843380119 cites W2047271695 @default.
• W843380119 cites W2048873522 @default.
• W843380119 cites W2052740154 @default.
• W843380119 cites W2054477929 @default.
• W843380119 cites W2060726822 @default.
• W843380119 cites W2063928917 @default.
• W843380119 cites W2066744493 @default.
• W843380119 cites W2071915231 @default.
• W843380119 cites W2072698217 @default.
• W843380119 cites W2074220434 @default.
• W843380119 cites W2076600697 @default.
• W843380119 cites W2079504814 @default.
• W843380119 cites W2080156358 @default.
• W843380119 cites W2082933376 @default.
• W843380119 cites W2082978552 @default.
• W843380119 cites W2087203385 @default.
• W843380119 cites W2087211932 @default.
• W843380119 cites W2089114529 @default.
• W843380119 cites W2092004965 @default.
• W843380119 cites W2092380504 @default.
• W843380119 cites W2092664596 @default.
• W843380119 cites W2093625343 @default.
• W843380119 cites W2094393302 @default.
• W843380119 cites W2096628719 @default.

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