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- W84351678 abstract "We analyzed the molecular diversity and evolution of the allelic variants in Yersinia pseudotuberculosis, Yersinia similis, and Yersinia pestis ompF gene. The average evolutionary divergence of ompF sequences was 0.041 ± 0.004. We revealed 30 unique ompF nucleotide alleles, which clustered into seven groups on the tree. We found that the Y. pseudotuberculosis ompF gene has evolved with nonrandom mutational rate under purifying selection in overall. Some surface loops (L1, L6, and L8) of the OmpF porin contain sites evolving under positive selection that indicates diversification (possibly by adaptive evolution) of the ompF gene of Y. pseudotuberculosis before emergence of Y. pestis. The species most likely have undergone different selective and evolutionary pressures, and thus evolved into diverse Y. pseudotuberculosis OmpF groups." @default.
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- W84351678 date "2012-01-01" @default.
- W84351678 modified "2023-10-16" @default.
- W84351678 title "Diversity and Adaptive Evolution of a Major Porin Gene (ompF) in Yersinia pseudotuberculosis" @default.
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- W84351678 doi "https://doi.org/10.1007/978-1-4614-3561-7_5" @default.
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