Matches in SemOpenAlex for { <https://semopenalex.org/work/W848294619> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W848294619 abstract "Waveform analysis of the fetal electrocardiogram has been studied since the early seventies from both physiological, signal processing and clinical aspects. It has been found to contain more useful information than the mere detection of RR-intervals (fetal heart rate), e.g., the ST-segment giving evidence of the ability of fetal myocardium to respond to the stress of labor. In the Swedish RCT, STAN S21® was used to monitor 4966 labors either with cardiotocography (CTG) only or with CTG in combination with the ST waveform analysis of the fetal electrocardiogram. A computerized algorithm, the ST Log, was used to identify the qualitative changes in the ST waveform automatically. Metabolic acidosis in cord artery blood defined as pH 12 mmol/L, decreased with 54% in the CTG+ST group according to intention to treat analysis. The number of operative deliveries for fetal distress decreased by 19%. A blinded assessment of neonatal outcome revealed an improvement of Apgar score 1 and 5 min, need for intensive care and neonatal encephalopathy in the group monitored with CTG in combination with ST waveform analysis. Detailed evaluation of the CTG- and ST-traces of the fetuses with acidemia at birth and three controls for each from the randomized controlled trial gave a higher inter-observer agreement for ST analysis than for CTG alone. ST waveform analysis in combination with CTG increased the specificity in identifying fetal hypoxia without losing sensitivity and gave a more conform indication to intervene. Interim analysis during the trial revealed several protocol violations and therefore additional educational efforts were made. The experimental study on fetal lamb using microdialysis technique to monitor cerebral energy metabolites simultaneously with ECG recording confirmed earlier studies on the increase in T/QRS ratio with asphyxia. The increase preceded the liberation of excitotoxic transmitters and signs of cell membrane degradation. Thus, during clinical conditions, STAN monitoring should indicate fetal hypoxia before irreversible brain damage has occurred. ST analysis of the fetal ECG in combination with CTG, reduced the incidence of newborns with adverse outcome and concomitantly reduced operative interventions for fetal distress — it is ready for introduction into standard clinical practice" @default.
- W848294619 created "2016-06-24" @default.
- W848294619 creator A5008686924 @default.
- W848294619 date "2003-01-01" @default.
- W848294619 modified "2023-10-17" @default.
- W848294619 title "Fetal ECG waveform analysis for intrapartum monitoring" @default.
- W848294619 hasPublicationYear "2003" @default.
- W848294619 type Work @default.
- W848294619 sameAs 848294619 @default.
- W848294619 citedByCount "2" @default.
- W848294619 countsByYear W8482946192012 @default.
- W848294619 crossrefType "dissertation" @default.
- W848294619 hasAuthorship W848294619A5008686924 @default.
- W848294619 hasConcept C126322002 @default.
- W848294619 hasConcept C164705383 @default.
- W848294619 hasConcept C168563851 @default.
- W848294619 hasConcept C172680121 @default.
- W848294619 hasConcept C2776046940 @default.
- W848294619 hasConcept C2777953023 @default.
- W848294619 hasConcept C2778052368 @default.
- W848294619 hasConcept C2778546801 @default.
- W848294619 hasConcept C2778964498 @default.
- W848294619 hasConcept C2779234561 @default.
- W848294619 hasConcept C2780109559 @default.
- W848294619 hasConcept C42219234 @default.
- W848294619 hasConcept C54355233 @default.
- W848294619 hasConcept C71924100 @default.
- W848294619 hasConcept C84393581 @default.
- W848294619 hasConcept C86803240 @default.
- W848294619 hasConceptScore W848294619C126322002 @default.
- W848294619 hasConceptScore W848294619C164705383 @default.
- W848294619 hasConceptScore W848294619C168563851 @default.
- W848294619 hasConceptScore W848294619C172680121 @default.
- W848294619 hasConceptScore W848294619C2776046940 @default.
- W848294619 hasConceptScore W848294619C2777953023 @default.
- W848294619 hasConceptScore W848294619C2778052368 @default.
- W848294619 hasConceptScore W848294619C2778546801 @default.
- W848294619 hasConceptScore W848294619C2778964498 @default.
- W848294619 hasConceptScore W848294619C2779234561 @default.
- W848294619 hasConceptScore W848294619C2780109559 @default.
- W848294619 hasConceptScore W848294619C42219234 @default.
- W848294619 hasConceptScore W848294619C54355233 @default.
- W848294619 hasConceptScore W848294619C71924100 @default.
- W848294619 hasConceptScore W848294619C84393581 @default.
- W848294619 hasConceptScore W848294619C86803240 @default.
- W848294619 hasLocation W8482946191 @default.
- W848294619 hasOpenAccess W848294619 @default.
- W848294619 hasPrimaryLocation W8482946191 @default.
- W848294619 hasRelatedWork W1559252597 @default.
- W848294619 hasRelatedWork W1900727340 @default.
- W848294619 hasRelatedWork W1995448022 @default.
- W848294619 hasRelatedWork W2001655165 @default.
- W848294619 hasRelatedWork W2035933865 @default.
- W848294619 hasRelatedWork W2058321105 @default.
- W848294619 hasRelatedWork W2103589761 @default.
- W848294619 hasRelatedWork W2104905586 @default.
- W848294619 hasRelatedWork W2106693398 @default.
- W848294619 hasRelatedWork W2402909705 @default.
- W848294619 hasRelatedWork W2409079671 @default.
- W848294619 hasRelatedWork W2416499577 @default.
- W848294619 hasRelatedWork W2417897452 @default.
- W848294619 hasRelatedWork W2516977313 @default.
- W848294619 hasRelatedWork W2614275448 @default.
- W848294619 hasRelatedWork W2624099367 @default.
- W848294619 hasRelatedWork W2915650312 @default.
- W848294619 hasRelatedWork W2974816245 @default.
- W848294619 hasRelatedWork W3009555108 @default.
- W848294619 hasRelatedWork W3095092532 @default.
- W848294619 isParatext "false" @default.
- W848294619 isRetracted "false" @default.
- W848294619 magId "848294619" @default.
- W848294619 workType "dissertation" @default.