Matches in SemOpenAlex for { <https://semopenalex.org/work/W850761736> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W850761736 abstract "Objective: Huntington’s Disease (HD), a devastating neurogenetic disorder, is clinically diagnosed by the presence of motor symptoms. However, cognitive deficits are present before motor symptoms appear. A large body of literature has shown the involvement of the fronto-striatal and fronto-parietal circuits in cognitive control. This study aims to investigate the role of the fronto-striatal circuit as a biomarker of the deficits in executive functions observed in HD. Methods: Twenty-six healthy adults and twenty-six HD patients underwent a functional magnetic resonance imaging involving a switching task. Two different approaches were applied: the standard general linear model and support vector machines, in order to investigate potential alterations of the fronto-striatal circuit engaged in cognitive control. Results: Using the general lineal model, we observed a gradually decreasing activity of the fronto-striatal circuits, following the disease progression. Additionally, different support vector machines based on the fronto-striatal activation pattern have allowed us to classify participants between controls and patients, although with an accuracy level lower than expected." @default.
- W850761736 created "2016-06-24" @default.
- W850761736 creator A5072315004 @default.
- W850761736 date "2015-04-30" @default.
- W850761736 modified "2023-09-26" @default.
- W850761736 title "Looking for neuroimaging biomarkers in Huntington Disease" @default.
- W850761736 cites W1560724230 @default.
- W850761736 cites W195739245 @default.
- W850761736 cites W1964357740 @default.
- W850761736 cites W1972498024 @default.
- W850761736 cites W1978763244 @default.
- W850761736 cites W1983672782 @default.
- W850761736 cites W1987326457 @default.
- W850761736 cites W2001830552 @default.
- W850761736 cites W2014022174 @default.
- W850761736 cites W2026071608 @default.
- W850761736 cites W2029563076 @default.
- W850761736 cites W2034294467 @default.
- W850761736 cites W2040305148 @default.
- W850761736 cites W2057607467 @default.
- W850761736 cites W2071579169 @default.
- W850761736 cites W2087157508 @default.
- W850761736 cites W2101721267 @default.
- W850761736 cites W2105037799 @default.
- W850761736 cites W2111464173 @default.
- W850761736 cites W2113642685 @default.
- W850761736 cites W2121705522 @default.
- W850761736 cites W2125789404 @default.
- W850761736 cites W2126350472 @default.
- W850761736 cites W2128552517 @default.
- W850761736 cites W2128634013 @default.
- W850761736 cites W2140082297 @default.
- W850761736 cites W2141459724 @default.
- W850761736 cites W2145217719 @default.
- W850761736 cites W2147362123 @default.
- W850761736 cites W2158485497 @default.
- W850761736 cites W2169735361 @default.
- W850761736 hasPublicationYear "2015" @default.
- W850761736 type Work @default.
- W850761736 sameAs 850761736 @default.
- W850761736 citedByCount "0" @default.
- W850761736 crossrefType "dissertation" @default.
- W850761736 hasAuthorship W850761736A5072315004 @default.
- W850761736 hasConcept C126322002 @default.
- W850761736 hasConcept C126838900 @default.
- W850761736 hasConcept C143409427 @default.
- W850761736 hasConcept C15744967 @default.
- W850761736 hasConcept C169760540 @default.
- W850761736 hasConcept C169900460 @default.
- W850761736 hasConcept C2775968953 @default.
- W850761736 hasConcept C2779134260 @default.
- W850761736 hasConcept C2780647506 @default.
- W850761736 hasConcept C2781197716 @default.
- W850761736 hasConcept C55493867 @default.
- W850761736 hasConcept C58693492 @default.
- W850761736 hasConcept C71924100 @default.
- W850761736 hasConcept C86803240 @default.
- W850761736 hasConceptScore W850761736C126322002 @default.
- W850761736 hasConceptScore W850761736C126838900 @default.
- W850761736 hasConceptScore W850761736C143409427 @default.
- W850761736 hasConceptScore W850761736C15744967 @default.
- W850761736 hasConceptScore W850761736C169760540 @default.
- W850761736 hasConceptScore W850761736C169900460 @default.
- W850761736 hasConceptScore W850761736C2775968953 @default.
- W850761736 hasConceptScore W850761736C2779134260 @default.
- W850761736 hasConceptScore W850761736C2780647506 @default.
- W850761736 hasConceptScore W850761736C2781197716 @default.
- W850761736 hasConceptScore W850761736C55493867 @default.
- W850761736 hasConceptScore W850761736C58693492 @default.
- W850761736 hasConceptScore W850761736C71924100 @default.
- W850761736 hasConceptScore W850761736C86803240 @default.
- W850761736 hasLocation W8507617361 @default.
- W850761736 hasOpenAccess W850761736 @default.
- W850761736 hasPrimaryLocation W8507617361 @default.
- W850761736 hasRelatedWork W1179800764 @default.
- W850761736 hasRelatedWork W1980478143 @default.
- W850761736 hasRelatedWork W2012622205 @default.
- W850761736 hasRelatedWork W2062719432 @default.
- W850761736 hasRelatedWork W2071579169 @default.
- W850761736 hasRelatedWork W2090849810 @default.
- W850761736 hasRelatedWork W2125285219 @default.
- W850761736 hasRelatedWork W2187060650 @default.
- W850761736 hasRelatedWork W2273150552 @default.
- W850761736 hasRelatedWork W2306440229 @default.
- W850761736 hasRelatedWork W2340545484 @default.
- W850761736 hasRelatedWork W2558470194 @default.
- W850761736 hasRelatedWork W2560429956 @default.
- W850761736 hasRelatedWork W2605759072 @default.
- W850761736 hasRelatedWork W2801970362 @default.
- W850761736 hasRelatedWork W2943678964 @default.
- W850761736 hasRelatedWork W2973870617 @default.
- W850761736 hasRelatedWork W3153960321 @default.
- W850761736 hasRelatedWork W3212071460 @default.
- W850761736 hasRelatedWork W2547999294 @default.
- W850761736 isParatext "false" @default.
- W850761736 isRetracted "false" @default.
- W850761736 magId "850761736" @default.
- W850761736 workType "dissertation" @default.