Matches in SemOpenAlex for { <https://semopenalex.org/work/W853270325> ?p ?o ?g. }
- W853270325 abstract "The present study was carried out to evaluate the protective effect of different statins on isoproterenol (ISO) induced myocardial necrosis. Atorvastatin, rosuvastatin, fluvastatin, simvastatin and pravastatin (10 mg/kg/day) were administered for 12 weeks. After pretreatment of 12 weeks myocardial necrosis was induced by subsequent injection of ISO (85 mg/kg/day, s.c.) to wistar rats. Serum biochemical parameters like glucose, lipid profile, cardiac markers and transaminases were evaluated. Animals were killed and heart was excised for histopathology and antioxidant study. Statins pretreated rats showed significant protection against ISO induced elevation in serum biochemical parameters and serum level of cardiac marker enzymes and transaminase level as compared to ISO control group. Mild to moderate protection was observed in different statins treated heart in histopathology and TTC stained sections. Result from our study also revealed that statins could efficiently protect against ISO intoxicated myocardial necrosis by impairing membrane bound enzyme integrity and endogenous antioxidant enzyme levels. Amongst all statins used, rosuvastatin and pravastatin were found to have maximum cardio-protective activity against ISO induced myocardial necrosis as compared to other statins." @default.
- W853270325 created "2016-06-24" @default.
- W853270325 creator A5001132909 @default.
- W853270325 creator A5022872391 @default.
- W853270325 creator A5027616482 @default.
- W853270325 creator A5045811922 @default.
- W853270325 creator A5087002800 @default.
- W853270325 date "2015-10-01" @default.
- W853270325 modified "2023-09-27" @default.
- W853270325 title "Comparative evaluation of HMG CoA reductase inhibitors in experimentally-induced myocardial necrosis: Biochemical, morphological and histological studies" @default.
- W853270325 cites W1499704472 @default.
- W853270325 cites W1750690213 @default.
- W853270325 cites W1775749144 @default.
- W853270325 cites W1899938340 @default.
- W853270325 cites W191793640 @default.
- W853270325 cites W1934999222 @default.
- W853270325 cites W1965309927 @default.
- W853270325 cites W1965579148 @default.
- W853270325 cites W1975842139 @default.
- W853270325 cites W1977644047 @default.
- W853270325 cites W1983577071 @default.
- W853270325 cites W1989810121 @default.
- W853270325 cites W1994946313 @default.
- W853270325 cites W2000077825 @default.
- W853270325 cites W2002226903 @default.
- W853270325 cites W2002498988 @default.
- W853270325 cites W2006088237 @default.
- W853270325 cites W2007206893 @default.
- W853270325 cites W2007622582 @default.
- W853270325 cites W2023956494 @default.
- W853270325 cites W2040312668 @default.
- W853270325 cites W2041755731 @default.
- W853270325 cites W2043203683 @default.
- W853270325 cites W2043869729 @default.
- W853270325 cites W2044468446 @default.
- W853270325 cites W2056126958 @default.
- W853270325 cites W2066040502 @default.
- W853270325 cites W2067477809 @default.
- W853270325 cites W2069132215 @default.
- W853270325 cites W2079351469 @default.
- W853270325 cites W2079730469 @default.
- W853270325 cites W2082198711 @default.
- W853270325 cites W2085068623 @default.
- W853270325 cites W2089385534 @default.
- W853270325 cites W2089660664 @default.
- W853270325 cites W2097764902 @default.
- W853270325 cites W2098017056 @default.
- W853270325 cites W2100879435 @default.
- W853270325 cites W2116404316 @default.
- W853270325 cites W2117622925 @default.
- W853270325 cites W2121037015 @default.
- W853270325 cites W2126372860 @default.
- W853270325 cites W2134497001 @default.
- W853270325 cites W2135812245 @default.
- W853270325 cites W2153435210 @default.
- W853270325 cites W2160919898 @default.
- W853270325 cites W2162393927 @default.
- W853270325 cites W2165592782 @default.
- W853270325 cites W2168103583 @default.
- W853270325 cites W2291450830 @default.
- W853270325 cites W2326786471 @default.
- W853270325 cites W2416476377 @default.
- W853270325 cites W2416730780 @default.
- W853270325 cites W2422958953 @default.
- W853270325 cites W2908505084 @default.
- W853270325 cites W393621279 @default.
- W853270325 cites W56878204 @default.
- W853270325 cites W77224165 @default.
- W853270325 cites W96106374 @default.
- W853270325 doi "https://doi.org/10.1016/j.ejphar.2015.07.024" @default.
- W853270325 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26169562" @default.
- W853270325 hasPublicationYear "2015" @default.
- W853270325 type Work @default.
- W853270325 sameAs 853270325 @default.
- W853270325 citedByCount "9" @default.
- W853270325 countsByYear W8532703252017 @default.
- W853270325 countsByYear W8532703252018 @default.
- W853270325 countsByYear W8532703252019 @default.
- W853270325 countsByYear W8532703252020 @default.
- W853270325 crossrefType "journal-article" @default.
- W853270325 hasAuthorship W853270325A5001132909 @default.
- W853270325 hasAuthorship W853270325A5022872391 @default.
- W853270325 hasAuthorship W853270325A5027616482 @default.
- W853270325 hasAuthorship W853270325A5045811922 @default.
- W853270325 hasAuthorship W853270325A5087002800 @default.
- W853270325 hasConcept C104950815 @default.
- W853270325 hasConcept C126322002 @default.
- W853270325 hasConcept C134018914 @default.
- W853270325 hasConcept C134651460 @default.
- W853270325 hasConcept C142724271 @default.
- W853270325 hasConcept C160160445 @default.
- W853270325 hasConcept C181199279 @default.
- W853270325 hasConcept C185592680 @default.
- W853270325 hasConcept C2776329913 @default.
- W853270325 hasConcept C2776692505 @default.
- W853270325 hasConcept C2776839432 @default.
- W853270325 hasConcept C2777318727 @default.
- W853270325 hasConcept C2777482532 @default.
- W853270325 hasConcept C2778163477 @default.
- W853270325 hasConcept C2778417548 @default.