Matches in SemOpenAlex for { <https://semopenalex.org/work/W85339462> ?p ?o ?g. }
- W85339462 endingPage "481" @default.
- W85339462 startingPage "465" @default.
- W85339462 abstract "Genome surveillance systems of higher organisms protect not only against intragenomic parasites such as retroposons and transposons but also against invasive DNAintroduced via genome transformation, resulting in (trans)gene silencing at both the transcriptional and posttranscriptionallevels. Transcriptional gene silencing of both bialaphos resistance and 8tt Cryi/lAcrystal toxin genes was encountered in experiments targeted to provide resistance to the rice water weevil. Extensive methylation of the transgenes, especially of the promoter elements, was evident. Germination of seedlings from silenced lines in the presence of 5-azacytidine (which prevents cytosine methylation) led to the reactivation of bialaphos resistance in progeny of silenced plants. The CaMV 355 promoter has been implicated in many instances of silencing and the possibility that some promoters are especially prone to silencing is supported by the finding that RCg2, a rice root-specific promoter, is silenced in more than 80% of transformants. Genes flanking RCg2/uidA are rarely silenced, showing that silencing can be highly targeted. Multicopy insertions are very susceptible to silencing and epistatic interactions between multicopy and single-copy inserts are documented. Several strategies to alleviate silencing have been considered, such as sequence diversification and flanking transgene inserts with matrix attachment regions. -" @default.
- W85339462 created "2016-06-24" @default.
- W85339462 creator A5007254401 @default.
- W85339462 creator A5015276796 @default.
- W85339462 creator A5021506562 @default.
- W85339462 creator A5030685993 @default.
- W85339462 creator A5035799410 @default.
- W85339462 creator A5038149016 @default.
- W85339462 creator A5045663522 @default.
- W85339462 creator A5052227484 @default.
- W85339462 creator A5058619440 @default.
- W85339462 creator A5059762495 @default.
- W85339462 creator A5065531457 @default.
- W85339462 creator A5072391827 @default.
- W85339462 creator A5072640596 @default.
- W85339462 creator A5088331911 @default.
- W85339462 date "2008-04-01" @default.
- W85339462 modified "2023-09-26" @default.
- W85339462 title "Gene silencing and its reactivation in transgenic rice" @default.
- W85339462 cites W1539503448 @default.
- W85339462 cites W1550720320 @default.
- W85339462 cites W1568285776 @default.
- W85339462 cites W157154316 @default.
- W85339462 cites W164447741 @default.
- W85339462 cites W1889938952 @default.
- W85339462 cites W1925002711 @default.
- W85339462 cites W1932753289 @default.
- W85339462 cites W1969553476 @default.
- W85339462 cites W1971823064 @default.
- W85339462 cites W1974698048 @default.
- W85339462 cites W1980912932 @default.
- W85339462 cites W1985099936 @default.
- W85339462 cites W198676265 @default.
- W85339462 cites W1997740256 @default.
- W85339462 cites W2007973509 @default.
- W85339462 cites W2020727217 @default.
- W85339462 cites W2025660464 @default.
- W85339462 cites W2031050539 @default.
- W85339462 cites W2037854651 @default.
- W85339462 cites W2039069559 @default.
- W85339462 cites W2041944855 @default.
- W85339462 cites W2044032739 @default.
- W85339462 cites W2046576215 @default.
- W85339462 cites W2046584121 @default.
- W85339462 cites W2052639867 @default.
- W85339462 cites W2059104421 @default.
- W85339462 cites W2079017128 @default.
- W85339462 cites W2080598025 @default.
- W85339462 cites W2082319283 @default.
- W85339462 cites W2084403120 @default.
- W85339462 cites W2087723521 @default.
- W85339462 cites W2088466817 @default.
- W85339462 cites W2091658754 @default.
- W85339462 cites W2106823467 @default.
- W85339462 cites W2109881276 @default.
- W85339462 cites W2113170874 @default.
- W85339462 cites W2116808387 @default.
- W85339462 cites W2118753423 @default.
- W85339462 cites W2120778382 @default.
- W85339462 cites W2122711136 @default.
- W85339462 cites W2127497651 @default.
- W85339462 cites W2128738669 @default.
- W85339462 cites W2131864855 @default.
- W85339462 cites W2141524685 @default.
- W85339462 cites W2142864992 @default.
- W85339462 cites W2145410762 @default.
- W85339462 cites W2150824061 @default.
- W85339462 cites W2151579372 @default.
- W85339462 cites W2158665961 @default.
- W85339462 cites W2164302672 @default.
- W85339462 cites W2165192624 @default.
- W85339462 cites W2166691486 @default.
- W85339462 cites W2166903671 @default.
- W85339462 cites W2299313072 @default.
- W85339462 cites W2364626012 @default.
- W85339462 cites W2431906485 @default.
- W85339462 cites W2468808683 @default.
- W85339462 cites W338068718 @default.
- W85339462 cites W53941272 @default.
- W85339462 doi "https://doi.org/10.1142/9789812814296_0031" @default.
- W85339462 hasPublicationYear "2008" @default.
- W85339462 type Work @default.
- W85339462 sameAs 85339462 @default.
- W85339462 citedByCount "1" @default.
- W85339462 crossrefType "book-chapter" @default.
- W85339462 hasAuthorship W85339462A5007254401 @default.
- W85339462 hasAuthorship W85339462A5015276796 @default.
- W85339462 hasAuthorship W85339462A5021506562 @default.
- W85339462 hasAuthorship W85339462A5030685993 @default.
- W85339462 hasAuthorship W85339462A5035799410 @default.
- W85339462 hasAuthorship W85339462A5038149016 @default.
- W85339462 hasAuthorship W85339462A5045663522 @default.
- W85339462 hasAuthorship W85339462A5052227484 @default.
- W85339462 hasAuthorship W85339462A5058619440 @default.
- W85339462 hasAuthorship W85339462A5059762495 @default.
- W85339462 hasAuthorship W85339462A5065531457 @default.
- W85339462 hasAuthorship W85339462A5072391827 @default.
- W85339462 hasAuthorship W85339462A5072640596 @default.