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- W853867718 abstract "Objective: To investigate the pathological roles of postnatally up-regulated alpha-fetoprotein (AFP) expression in ZBTB20 knockout mice in postnatal growth retardation, metabolic dysfunction, and pre-mature mortality. Methods: ZBTB20 and AFP knockout mice were generated by crossbreeding ZBTB20 knockout mice with AFP knockout mice. The postnatal growth, survival rate, and blood glucose of ZBTB20/AFP double knockout mice were observed and compared with those of ZBTB20 knockout mice. Results: There were no significant differences in postnatal growth, survival, and glucose homeostasis between ZBTB20/AFP doube knockout mice and ZBTB20 knockout mice. Conclusion: The postnatally upregulated liver AFP in ZBTB20 knockout mice is not associated with the growth retardation, hypoglycemia, or pre-mature mortality." @default.
- W853867718 created "2016-06-24" @default.
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- W853867718 date "2010-12-01" @default.
- W853867718 modified "2023-09-25" @default.
- W853867718 title "Pathological implication of postnatally up-regulated AFP expression in ZBTB20 knockout neonatal mice" @default.
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- W853867718 doi "https://doi.org/10.3724/sp.j.1008.2010.01045" @default.
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