Matches in SemOpenAlex for { <https://semopenalex.org/work/W85391719> ?p ?o ?g. }
- W85391719 endingPage "75" @default.
- W85391719 startingPage "259" @default.
- W85391719 abstract "The immunochemical depletion from serum of C3b inactivator (KAF) has been performed using purified F(ab′)2 antibody. In vitro KAF depletion leads to spontaneous activation of the `alternate pathway of complement fixation' as evidenced by conversion of glycine-rich β-glycoprotein, depletion of cobra venom factor—C3 proactivator and conversion of C3.The status of the complement system following in vitro KAF depletion accurately mimics that found in vivo in the unique KAF-deficient patient.The activation of the alternative pathway whether by KAF depletion or by conventional alternative pathway activators is prevented by the immunochemical depletion of C3. It therefore appears that the alternative pathway is essentially a C3b-feedback pathway which is normally controlled by the activity of KAF." @default.
- W85391719 created "2016-06-24" @default.
- W85391719 creator A5015981919 @default.
- W85391719 creator A5078864099 @default.
- W85391719 date "1973-02-01" @default.
- W85391719 modified "2023-10-18" @default.
- W85391719 title "The alternate pathway of complement activation. The role of C3 and its inactivator (KAF)." @default.
- W85391719 cites W1488807000 @default.
- W85391719 cites W1493618746 @default.
- W85391719 cites W1495213486 @default.
- W85391719 cites W1544793479 @default.
- W85391719 cites W1548950760 @default.
- W85391719 cites W1898101441 @default.
- W85391719 cites W1905838633 @default.
- W85391719 cites W1952707006 @default.
- W85391719 cites W1967833287 @default.
- W85391719 cites W1975908451 @default.
- W85391719 cites W1978058154 @default.
- W85391719 cites W1996820575 @default.
- W85391719 cites W2000842634 @default.
- W85391719 cites W2025386975 @default.
- W85391719 cites W2032339060 @default.
- W85391719 cites W2032566319 @default.
- W85391719 cites W2052308950 @default.
- W85391719 cites W2065581822 @default.
- W85391719 cites W2086165385 @default.
- W85391719 cites W2103464375 @default.
- W85391719 cites W2157353912 @default.
- W85391719 cites W2336670488 @default.
- W85391719 cites W2396014084 @default.
- W85391719 cites W2403387312 @default.
- W85391719 cites W2416457976 @default.
- W85391719 cites W2428349926 @default.
- W85391719 cites W2442464748 @default.
- W85391719 cites W2620799180 @default.
- W85391719 cites W1891397857 @default.
- W85391719 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1423020" @default.
- W85391719 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4632688" @default.
- W85391719 hasPublicationYear "1973" @default.
- W85391719 type Work @default.
- W85391719 sameAs 85391719 @default.
- W85391719 citedByCount "64" @default.
- W85391719 countsByYear W853917192016 @default.
- W85391719 countsByYear W853917192018 @default.
- W85391719 countsByYear W853917192021 @default.
- W85391719 countsByYear W853917192022 @default.
- W85391719 crossrefType "journal-article" @default.
- W85391719 hasAuthorship W85391719A5015981919 @default.
- W85391719 hasAuthorship W85391719A5078864099 @default.
- W85391719 hasConcept C104317684 @default.
- W85391719 hasConcept C108625454 @default.
- W85391719 hasConcept C111684460 @default.
- W85391719 hasConcept C112313634 @default.
- W85391719 hasConcept C127716648 @default.
- W85391719 hasConcept C159654299 @default.
- W85391719 hasConcept C171279029 @default.
- W85391719 hasConcept C185592680 @default.
- W85391719 hasConcept C188082640 @default.
- W85391719 hasConcept C189446657 @default.
- W85391719 hasConcept C202751555 @default.
- W85391719 hasConcept C203014093 @default.
- W85391719 hasConcept C207001950 @default.
- W85391719 hasConcept C54355233 @default.
- W85391719 hasConcept C55493867 @default.
- W85391719 hasConcept C86803240 @default.
- W85391719 hasConcept C95444343 @default.
- W85391719 hasConceptScore W85391719C104317684 @default.
- W85391719 hasConceptScore W85391719C108625454 @default.
- W85391719 hasConceptScore W85391719C111684460 @default.
- W85391719 hasConceptScore W85391719C112313634 @default.
- W85391719 hasConceptScore W85391719C127716648 @default.
- W85391719 hasConceptScore W85391719C159654299 @default.
- W85391719 hasConceptScore W85391719C171279029 @default.
- W85391719 hasConceptScore W85391719C185592680 @default.
- W85391719 hasConceptScore W85391719C188082640 @default.
- W85391719 hasConceptScore W85391719C189446657 @default.
- W85391719 hasConceptScore W85391719C202751555 @default.
- W85391719 hasConceptScore W85391719C203014093 @default.
- W85391719 hasConceptScore W85391719C207001950 @default.
- W85391719 hasConceptScore W85391719C54355233 @default.
- W85391719 hasConceptScore W85391719C55493867 @default.
- W85391719 hasConceptScore W85391719C86803240 @default.
- W85391719 hasConceptScore W85391719C95444343 @default.
- W85391719 hasIssue "2" @default.
- W85391719 hasLocation W853917191 @default.
- W85391719 hasOpenAccess W85391719 @default.
- W85391719 hasPrimaryLocation W853917191 @default.
- W85391719 hasRelatedWork W1992523389 @default.
- W85391719 hasRelatedWork W2070010238 @default.
- W85391719 hasRelatedWork W2413504655 @default.
- W85391719 hasRelatedWork W2420968053 @default.
- W85391719 hasRelatedWork W2427256455 @default.
- W85391719 hasRelatedWork W2752956711 @default.
- W85391719 hasRelatedWork W2794130642 @default.
- W85391719 hasRelatedWork W2808717877 @default.
- W85391719 hasRelatedWork W2883340563 @default.
- W85391719 hasRelatedWork W3022882395 @default.
- W85391719 hasVolume "24" @default.