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- W85532459 abstract "Objective To optimize the formulation of nifedipine sustained release liquid filled capsules by orthogonal design.Methods The single-factor experiment method and formulation screening were used to study the influence of contents of S-40,stearic acid and starch.Three factors and three levels orthogonal experiment design was used to screen the optimum proportion of formulation.Results The best formulation of nifedipine sustained release liquid filled capsules was Nif 20g,S-40 320 g and starch 20 g in 1 000 capsules by optimization.Conclusion According to optimization formulation,500 nifedipine sustained release liquid filled capsules were prepared,and the release and stability of Nif was good." @default.
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- W85532459 date "2009-01-01" @default.
- W85532459 modified "2023-09-28" @default.
- W85532459 title "Preparation of nifedipine sustained release liquid filled capsules." @default.
- W85532459 hasPublicationYear "2009" @default.
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