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- W855428602 startingPage "e1080" @default.
- W855428602 abstract "Carcinoma of the prostate is the most commonly diagnosed malignancy and the third leading cause of mortality in New Zealand men, making it a significant health issue in this country. Global distribution patterns suggest that diet and lifestyle factors may be linked to the development and progression of this cancer. Twenty men with diagnosed prostate cancer adhered to a Mediterranean diet, with specific adaptations, for three months. Prostate-specific antigen, C-reactive protein and DNA damage were evaluated at baseline and after three months of following the diet. Dietary data were collated from diet diaries and an adaptation of a validated Mediterranean diet questionnaire. A significant reduction in DNA damage compared to baseline was apparent, with particular benefit noted for overall adherence to the diet (p = 0.013), increased intake of folate (p = 0.023), vitamin C (p = 0.007), legumes (p = 0.004) and green tea (p = 0.002). Higher intakes of red meat and dairy products were inversely associated with DNA damage (p = 0.003 and p = 0.008 respectively). The results from this small feasibility study suggest that a high-antioxidant diet, modelled on Mediterranean traditions, may be of benefit for men with prostate cancer. Protection against DNA damage appears to be associated with the diet implemented, ostensibly due to reduction in reactive oxidant species. These findings warrant further exploration in a longer trial, with a larger cohort." @default.
- W855428602 created "2016-06-24" @default.
- W855428602 creator A5020173949 @default.
- W855428602 creator A5022138320 @default.
- W855428602 creator A5035694502 @default.
- W855428602 creator A5057733198 @default.
- W855428602 creator A5079854311 @default.
- W855428602 date "2015-07-02" @default.
- W855428602 modified "2023-10-14" @default.
- W855428602 title "A pilot study to investigate if New Zealand men with prostate cancer benefit from a Mediterranean-style diet" @default.
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