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- W856909250 abstract "Medullary thyroid cancer accounts for about 6–10% of all thyroid malignancies. About 70% of patients with medullary thyroid cancer have sporadic disease and 30% have either familial MTC, MEN 2A or MEN 2B (1). The different clinical types of MTC are associated with different but specific ret point mutations. About 50% of patients with sporadic MTC also have somatic ret mutations in their medullary cancers that appear to correlate with specific mutations (2). For example, the 918 mutation that is associated with MEN 2B when found as a somatic mutation in the tumor of patients with medullary thyroid cancer is associated with a worse prognosis (2).KeywordsParathyroid GlandMedullary Thyroid CarcinomaMedullary ThyroidMedullary Thyroid CancerMedullary CarcinomaThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves." @default.
- W856909250 created "2016-06-24" @default.
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- W856909250 date "2000-01-01" @default.
- W856909250 modified "2023-09-24" @default.
- W856909250 title "Management of Medullary Carcinoma of the Thyroid" @default.
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- W856909250 doi "https://doi.org/10.1007/978-1-59259-199-2_45" @default.
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