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- W8587087 abstract "The immune system has evolved to protect us from pathogens [1]. A great number of infectious microbes, viruses, bacteria, fungi, protozoa and multicellular parasites are present in our environment. The cells which mediate immunity include lymphocytes and phagocytes. Lymphocytes recognize antigens on pathogens. Phagocytes internalize the pathogens and degrade them. Any immune response involves, first, a recognition of the pathogen or other foreign material, and second, a reaction to eliminate it (Fig.1). Different types of immune responses fall into two categories: innate (or non-adaptive) immune responses, and adaptive immune response. Specificity and memory are two essential features of adaptive immune responses. Lymphocytes have specialized functions. B cells make antibodies [2]; cytotoxic T (CD8)cells kill virally infected cells; helper T cells subdivided into Th1 and Th2 coordinate the immune response by directing cell-cell interactions and the release of cytokines, which help B cells to make antibodies [3]. Antigens are molecules which are recognized by receptors on lymphocytes [4]. B lymphocytes usually recognize intact antigen molecules, while T lymphocytes recognize antigen fragments on the surface of other cells. Clonal selection involves recognition of antigen by particular lymphocytes; this leads to clonal expansion and differentiation to effector and memory cells. The immune system may break down. This can lead to immunodeficiency or hypersensitivity diseases or to autoimmune diseases." @default.
- W8587087 created "2016-06-24" @default.
- W8587087 creator A5042435666 @default.
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- W8587087 date "2001-01-01" @default.
- W8587087 modified "2023-09-25" @default.
- W8587087 title "Lymphocyte Activation in Acute Coronary Syndromes" @default.
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- W8587087 doi "https://doi.org/10.1007/978-3-0348-8239-2_11" @default.
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