FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W859618145> ?p ?o ?g. }

• W859618145 endingPage "2929" @default.
• W859618145 startingPage "2923" @default.
• W859618145 abstract "Research Article1 September 1990free access Molecular cloning, primary structure and expression of the human X linked A1S9 gene cDNA which complements the ts A1S9 mouse L cell defect in DNA replication. E. Zacksenhaus E. Zacksenhaus Department of Microbiology, Faculty of Medicine, University of Toronto, Ontario, Canada. Search for more papers by this author R. Sheinin R. Sheinin Department of Microbiology, Faculty of Medicine, University of Toronto, Ontario, Canada. Search for more papers by this author E. Zacksenhaus E. Zacksenhaus Department of Microbiology, Faculty of Medicine, University of Toronto, Ontario, Canada. Search for more papers by this author R. Sheinin R. Sheinin Department of Microbiology, Faculty of Medicine, University of Toronto, Ontario, Canada. Search for more papers by this author Author Information E. Zacksenhaus1 and R. Sheinin1 1Department of Microbiology, Faculty of Medicine, University of Toronto, Ontario, Canada. The EMBO Journal (1990)9:2923-2929https://doi.org/10.1002/j.1460-2075.1990.tb07483.x PDFDownload PDF of article text and main figures. ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InMendeleyWechatReddit Figures & Info The temperature-sensitive ts A1S9 mutation of mouse L cells was previously shown to affect nuclear DNA replication and to be complemented by active and inactive human X chromosomes in human-ts A1S9 somatic cell hybrids. We report the isolation of cDNA clones which correct the ts A1S9 lesion, using as a probe a genomic fragment derived from the human A1S9 locus. The nucleotide sequence of the A1S9 cDNA encompasses a single open reading frame of 2409 bp which could encode a heretofore unreported protein of 90 393 daltons. Southern blot hybridization of the A1S9 cDNA probe with DNA from various species revealed homologous sequences in vertebrates but not in yeast. Northern blot analysis of serum-starved, synchronized cells demonstrated that the A1S9 gene was expressed at a relatively low level in quiescent cells and at a higher and constant level throughout the cell cycle. Human cell lines harbouring increasing numbers of inactive X chromosomes (47, XXX, 49, XXXXX) were found to express the A1S9 gene at the same level as control cells (45, X), suggesting that the gene does not escape X chromosome inactivation. Previous ArticleNext Article Volume 9Issue 91 September 1990In this issue RelatedDetailsLoading ..." @default.
• W859618145 created "2016-06-24" @default.
• W859618145 creator A5060217079 @default.
• W859618145 creator A5083668108 @default.
• W859618145 date "1990-09-01" @default.
• W859618145 modified "2023-09-24" @default.
• W859618145 title "Molecular cloning, primary structure and expression of the human X linked A1S9 gene cDNA which complements the ts A1S9 mouse L cell defect in DNA replication." @default.
• W859618145 cites W1028859 @default.
• W859618145 cites W1518322853 @default.
• W859618145 cites W1546027468 @default.
• W859618145 cites W1755272434 @default.
• W859618145 cites W1787741637 @default.
• W859618145 cites W1799709247 @default.
• W859618145 cites W1848751398 @default.
• W859618145 cites W1859008192 @default.
• W859618145 cites W1918119607 @default.
• W859618145 cites W1965372133 @default.
• W859618145 cites W1969883059 @default.
• W859618145 cites W1972986614 @default.
• W859618145 cites W1974780785 @default.
• W859618145 cites W1975304761 @default.
• W859618145 cites W1993028041 @default.
• W859618145 cites W1995339904 @default.
• W859618145 cites W1996700508 @default.
• W859618145 cites W2009105413 @default.
• W859618145 cites W2012412628 @default.
• W859618145 cites W2014669590 @default.
• W859618145 cites W2029334974 @default.
• W859618145 cites W2033967561 @default.
• W859618145 cites W2044879696 @default.
• W859618145 cites W2046359892 @default.
• W859618145 cites W2051406511 @default.
• W859618145 cites W2060364832 @default.
• W859618145 cites W2065614910 @default.
• W859618145 cites W2073077875 @default.
• W859618145 cites W2077297615 @default.
• W859618145 cites W2079507934 @default.
• W859618145 cites W2082604031 @default.
• W859618145 cites W2083293254 @default.
• W859618145 cites W2086471138 @default.
• W859618145 cites W2086870938 @default.
• W859618145 cites W2086955288 @default.
• W859618145 cites W2087656195 @default.
• W859618145 cites W2091412269 @default.
• W859618145 cites W2092476418 @default.
• W859618145 cites W2108840105 @default.
• W859618145 cites W2115494657 @default.
• W859618145 cites W2126420387 @default.
• W859618145 cites W2132781864 @default.
• W859618145 cites W2133783176 @default.
• W859618145 cites W2134812217 @default.
• W859618145 cites W2159847993 @default.
• W859618145 cites W2161247979 @default.
• W859618145 cites W2173844423 @default.
• W859618145 cites W2176106422 @default.
• W859618145 cites W2176126518 @default.
• W859618145 cites W281591248 @default.
• W859618145 cites W3024125022 @default.
• W859618145 cites W415599051 @default.
• W859618145 cites W66940515 @default.
• W859618145 cites W76301803 @default.
• W859618145 cites W80901980 @default.
• W859618145 cites W838635636 @default.
• W859618145 doi "https://doi.org/10.1002/j.1460-2075.1990.tb07483.x" @default.
• W859618145 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/552008" @default.
• W859618145 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2390975" @default.
• W859618145 hasPublicationYear "1990" @default.
• W859618145 type Work @default.
• W859618145 sameAs 859618145 @default.
• W859618145 citedByCount "61" @default.
• W859618145 countsByYear W8596181452012 @default.
• W859618145 countsByYear W8596181452014 @default.
• W859618145 countsByYear W8596181452016 @default.
• W859618145 countsByYear W8596181452017 @default.
• W859618145 crossrefType "journal-article" @default.
• W859618145 hasAuthorship W859618145A5060217079 @default.
• W859618145 hasAuthorship W859618145A5083668108 @default.
• W859618145 hasBestOaLocation W8596181451 @default.
• W859618145 hasConcept C104317684 @default.
• W859618145 hasConcept C153911025 @default.
• W859618145 hasConcept C167625842 @default.
• W859618145 hasConcept C187882448 @default.
• W859618145 hasConcept C19924922 @default.
• W859618145 hasConcept C47289529 @default.
• W859618145 hasConcept C54355233 @default.
• W859618145 hasConcept C552990157 @default.
• W859618145 hasConcept C86803240 @default.
• W859618145 hasConceptScore W859618145C104317684 @default.
• W859618145 hasConceptScore W859618145C153911025 @default.
• W859618145 hasConceptScore W859618145C167625842 @default.
• W859618145 hasConceptScore W859618145C187882448 @default.
• W859618145 hasConceptScore W859618145C19924922 @default.
• W859618145 hasConceptScore W859618145C47289529 @default.
• W859618145 hasConceptScore W859618145C54355233 @default.
• W859618145 hasConceptScore W859618145C552990157 @default.
• W859618145 hasConceptScore W859618145C86803240 @default.
• W859618145 hasIssue "9" @default.
• W859618145 hasLocation W8596181451 @default.

• next