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- W85993810 abstract "According to the authors the best designation of Ritter's disease would be staphilococcic epidermal exfoliation SEE. The physiopathological and agnoslogical basis for this denomination could be the following: 1st The S. aureus is the ehtiological agent of the SSE in man. The Koch postulates necessary to confirm this hypothesis have been accomplished. 2nd Staphylococcus aureus produces a thermostable toxin that is active indepently of the staphilococcus and gives rise to the separation of the cells of the stratum granulosus of the epidermis and eventually exfoliation in suckling babies and in the newborn mouse. 3rd The Staphylococcus aureus may be present on the skin or in other localisations such as the bowel or pharinx. 4th The viable S. aureus when administered subcutaneously to the adult mice gives rise to lesions clinically and histologically similar to the impetigo observed in children. 5th The S. aureus killed by means of autoclave (that is, the staphylococcic toxine by itself does not give rise to any lesion when administered to the healthy adult mouse). Neijther has the SEE been observed in healthy adult man. The authors reach the conclusion that the SSE and the toxic epidermal necrolysis are basically different according to the histopathology therapeutic response and prognosis and they must be considered as independant entities." @default.
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- W85993810 date "1976-01-01" @default.
- W85993810 modified "2023-09-23" @default.
- W85993810 title "[Staphylococcal epidermal exfoliation (Ritter's disease)]." @default.
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