Matches in SemOpenAlex for { <https://semopenalex.org/work/W861315875> ?p ?o ?g. }
Showing items 1 to 61 of
61
with 100 items per page.
- W861315875 abstract "This chapter talks about competence and transformation in their bacterial senses (competence to take up DNA, genetic transformation by recombination with this DNA) and also about the skills and sudden changes at the heart of a research career. Thus, one of the three histories is the author's own—how he came to work on DNA uptake, why he thinks it is so important. Another is the history of research into competence and transformation--what has been learned and where it has led. The third is the evolutionary history of the phenomena themselves--when and how the ability to actively take up DNA evolved, how often it leads to genetic transformation, and what this has contributed to bacterial evolution. The author knew from introductory biology that the first evidence DNA carried genetic information was the ability of Streptococcus pneumoniae to change its genes by taking up DNA from its surroundings. Since then a number of bacteria had been shown to take up fragments of chromosomal DNA and recombine them into their chromosomes, although only a few (the gram-positive S. pneumoniae and Bacillus subtilis and the gram-negative Haemophilus influenzae) had been studied in any detail. The author's tests, using agents that produced single-strand or double-strand damage, showed that DNA damage did not induce competence in either H. influenzae or B. subtilis. Proponents of the transformation function for competence argue that the sequence bias of the uptake machinery is an adaptation for transformation." @default.
- W861315875 created "2016-06-24" @default.
- W861315875 creator A5075013024 @default.
- W861315875 date "2014-04-09" @default.
- W861315875 modified "2023-09-25" @default.
- W861315875 title "Three Histories of Competence and Transformation" @default.
- W861315875 cites W1565578508 @default.
- W861315875 cites W1998485402 @default.
- W861315875 cites W2017433972 @default.
- W861315875 cites W2048540261 @default.
- W861315875 cites W2090952227 @default.
- W861315875 cites W2114072618 @default.
- W861315875 cites W2139216324 @default.
- W861315875 cites W2158815846 @default.
- W861315875 cites W2245214327 @default.
- W861315875 doi "https://doi.org/10.1128/9781555816810.ch28" @default.
- W861315875 hasPublicationYear "2014" @default.
- W861315875 type Work @default.
- W861315875 sameAs 861315875 @default.
- W861315875 citedByCount "0" @default.
- W861315875 crossrefType "book-chapter" @default.
- W861315875 hasAuthorship W861315875A5075013024 @default.
- W861315875 hasConcept C100521375 @default.
- W861315875 hasConcept C104317684 @default.
- W861315875 hasConcept C15744967 @default.
- W861315875 hasConcept C204241405 @default.
- W861315875 hasConcept C2776925733 @default.
- W861315875 hasConcept C2777272437 @default.
- W861315875 hasConcept C2781253189 @default.
- W861315875 hasConcept C523546767 @default.
- W861315875 hasConcept C54355233 @default.
- W861315875 hasConcept C552990157 @default.
- W861315875 hasConcept C77805123 @default.
- W861315875 hasConcept C86803240 @default.
- W861315875 hasConceptScore W861315875C100521375 @default.
- W861315875 hasConceptScore W861315875C104317684 @default.
- W861315875 hasConceptScore W861315875C15744967 @default.
- W861315875 hasConceptScore W861315875C204241405 @default.
- W861315875 hasConceptScore W861315875C2776925733 @default.
- W861315875 hasConceptScore W861315875C2777272437 @default.
- W861315875 hasConceptScore W861315875C2781253189 @default.
- W861315875 hasConceptScore W861315875C523546767 @default.
- W861315875 hasConceptScore W861315875C54355233 @default.
- W861315875 hasConceptScore W861315875C552990157 @default.
- W861315875 hasConceptScore W861315875C77805123 @default.
- W861315875 hasConceptScore W861315875C86803240 @default.
- W861315875 hasLocation W8613158751 @default.
- W861315875 hasOpenAccess W861315875 @default.
- W861315875 hasPrimaryLocation W8613158751 @default.
- W861315875 hasRelatedWork W1983897678 @default.
- W861315875 hasRelatedWork W1984960881 @default.
- W861315875 hasRelatedWork W1995123629 @default.
- W861315875 hasRelatedWork W2042427533 @default.
- W861315875 hasRelatedWork W2063349466 @default.
- W861315875 hasRelatedWork W2124190944 @default.
- W861315875 hasRelatedWork W2321203761 @default.
- W861315875 hasRelatedWork W2425868650 @default.
- W861315875 isParatext "false" @default.
- W861315875 isRetracted "false" @default.
- W861315875 magId "861315875" @default.
- W861315875 workType "book-chapter" @default.