Matches in SemOpenAlex for { <https://semopenalex.org/work/W86131973> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W86131973 endingPage "205" @default.
- W86131973 startingPage "201" @default.
- W86131973 abstract "This retrospective study aims to report on the use of dexmedetomidine to treat opioid withdrawal following sedation during mechanical ventilation in a cohort of infants. Seven infants in the pediatric intensive care unit of a tertiary care center, ranging in age from three to 24 months (12.4 ± 8.2 months) and in weight from 4.6 to 15.4 kgs (9.9 ± 4.2 kgs), had received a continuous fentanyl infusion, supplemented with intermittent doses of midazolam for sedation, during mechanical ventilation. Withdrawal was documented by a Finnegan score ³ 12. Dexmedetomidine was administered as a loading dose of 0.5 mg/kg/hr, followed by an infusion of 0.5 mg/kg/hr.Dexmedetomidine effectively controlled the signs and symptoms of withdrawal in the seven patients. Subsequent Finnegan scores were £ 7 at all times (median 4, range 1 to 7). Two patients required a repeat of the loading dose and an increase of the infusion to 0.7 mg/kg/hr. These two patients had received higher doses of fentanyl than the other five patients (8.5 ± 0.7 versus 4.6 ± 0.5 mg/kg/hr, p < 0.0005). No adverse hemodynamic or respiratory effects related to dexmedetomidine were noted.This report involves the largest cohort of patients to receive dexmedetomidine in the treatment of withdrawal following opioid and benzodiazepine sedation during mechanical ventilation. We conclude that dexmedetomidine offers a viable option for such issues in the pediatric intensive care unit (PICU) setting." @default.
- W86131973 created "2016-06-24" @default.
- W86131973 creator A5048394709 @default.
- W86131973 date "2006-07-01" @default.
- W86131973 modified "2023-10-18" @default.
- W86131973 title "Dexmedetomidine to treat opioid withdrawal in infants following prolonged sedation in the pediatric ICU" @default.
- W86131973 doi "https://doi.org/10.5055/jom.2006.0031" @default.
- W86131973 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17319480" @default.
- W86131973 hasPublicationYear "2006" @default.
- W86131973 type Work @default.
- W86131973 sameAs 86131973 @default.
- W86131973 citedByCount "70" @default.
- W86131973 countsByYear W861319732012 @default.
- W86131973 countsByYear W861319732013 @default.
- W86131973 countsByYear W861319732014 @default.
- W86131973 countsByYear W861319732015 @default.
- W86131973 countsByYear W861319732016 @default.
- W86131973 countsByYear W861319732017 @default.
- W86131973 countsByYear W861319732018 @default.
- W86131973 countsByYear W861319732019 @default.
- W86131973 countsByYear W861319732020 @default.
- W86131973 countsByYear W861319732021 @default.
- W86131973 countsByYear W861319732022 @default.
- W86131973 countsByYear W861319732023 @default.
- W86131973 crossrefType "journal-article" @default.
- W86131973 hasAuthorship W86131973A5048394709 @default.
- W86131973 hasBestOaLocation W861319731 @default.
- W86131973 hasConcept C126322002 @default.
- W86131973 hasConcept C141071460 @default.
- W86131973 hasConcept C167135981 @default.
- W86131973 hasConcept C170493617 @default.
- W86131973 hasConcept C177713679 @default.
- W86131973 hasConcept C187212893 @default.
- W86131973 hasConcept C2776376669 @default.
- W86131973 hasConcept C2776814716 @default.
- W86131973 hasConcept C2777080012 @default.
- W86131973 hasConcept C2778000748 @default.
- W86131973 hasConcept C2778939556 @default.
- W86131973 hasConcept C2781063702 @default.
- W86131973 hasConcept C2781072394 @default.
- W86131973 hasConcept C2781302539 @default.
- W86131973 hasConcept C35294091 @default.
- W86131973 hasConcept C42219234 @default.
- W86131973 hasConcept C71924100 @default.
- W86131973 hasConcept C72563966 @default.
- W86131973 hasConceptScore W86131973C126322002 @default.
- W86131973 hasConceptScore W86131973C141071460 @default.
- W86131973 hasConceptScore W86131973C167135981 @default.
- W86131973 hasConceptScore W86131973C170493617 @default.
- W86131973 hasConceptScore W86131973C177713679 @default.
- W86131973 hasConceptScore W86131973C187212893 @default.
- W86131973 hasConceptScore W86131973C2776376669 @default.
- W86131973 hasConceptScore W86131973C2776814716 @default.
- W86131973 hasConceptScore W86131973C2777080012 @default.
- W86131973 hasConceptScore W86131973C2778000748 @default.
- W86131973 hasConceptScore W86131973C2778939556 @default.
- W86131973 hasConceptScore W86131973C2781063702 @default.
- W86131973 hasConceptScore W86131973C2781072394 @default.
- W86131973 hasConceptScore W86131973C2781302539 @default.
- W86131973 hasConceptScore W86131973C35294091 @default.
- W86131973 hasConceptScore W86131973C42219234 @default.
- W86131973 hasConceptScore W86131973C71924100 @default.
- W86131973 hasConceptScore W86131973C72563966 @default.
- W86131973 hasIssue "4" @default.
- W86131973 hasLocation W861319731 @default.
- W86131973 hasLocation W861319732 @default.
- W86131973 hasOpenAccess W86131973 @default.
- W86131973 hasPrimaryLocation W861319731 @default.
- W86131973 hasRelatedWork W1990997597 @default.
- W86131973 hasRelatedWork W2186398722 @default.
- W86131973 hasRelatedWork W2333479277 @default.
- W86131973 hasRelatedWork W2348523392 @default.
- W86131973 hasRelatedWork W2884670186 @default.
- W86131973 hasRelatedWork W3030767958 @default.
- W86131973 hasRelatedWork W3030850133 @default.
- W86131973 hasRelatedWork W4200501500 @default.
- W86131973 hasRelatedWork W4280587118 @default.
- W86131973 hasRelatedWork W4306405655 @default.
- W86131973 hasVolume "2" @default.
- W86131973 isParatext "false" @default.
- W86131973 isRetracted "false" @default.
- W86131973 magId "86131973" @default.
- W86131973 workType "article" @default.