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- W862012180 abstract "This chapter provides an overview of centriole and centrosome autoantibodies. In most cell types, the number of centrosome/centrioles detected by indirect immunofluorescence correlates with the stage of the cell cycle. A number of centrosome antigens are identified with human autoimmune sera. In the largest study of sera from patients with the scleroderma spectrum of diseases (SSD), anticentrosome/centriole were found in one secondary Raynaud's phenomenon (RP) patient but not in patients meeting classification criteria for mixed connective tissue disease or primary RP. Centriole and centrosome antibodies are rare. They occur in approximately 0.1% of female blood donors and in 0.4–5% of SSD sera. Centriole antibodies can antedate the clinical diagnosis of scleroderma by several years." @default.
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- W862012180 modified "2023-10-16" @default.
- W862012180 title "Centriole and Centrosome Autoantibodies" @default.
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- W862012180 doi "https://doi.org/10.1016/b978-044482383-0/50024-8" @default.
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