FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W86352707> ?p ?o ?g. }

• W86352707 endingPage "8" @default.
• W86352707 startingPage "1211" @default.
• W86352707 abstract "Fifty percent of men over the age of fifty are diagnosed benign prostate hyperplasia. It is caused by disorders in the balance of androgens and estrogens, depending on the activity of sexual glands; therefore it is advisable to examine the functioning of these organs and to determine the pathogenetic mechanism of effect of this pathology. The antiandrogenic effect of Echinacea preparations was examined in our previous study and hypoplasia of histological structures and the mass reduction of prostate were determined. This encouraged more detailed investigation of the effect of the preparation directly to the organs, participating in the synthesis of the male hormone - testosterone. The effect of Echinacea extract on a testicle and epididymis was examined, the mass of these organs was determined, the proportion between the mass of the organ and the mass of a body was calculated, the changes in histological structures were evaluated in this study.Experiments with the Wistar line 3-month-old male rats were carried out. There were three experimental groups of rats. The first one was control group. The rats of the second group were fed on the usual food enriched with the Echinacea extract additive with the proportion of 50 mg/kg for 4 weeks. The rats in the third group were fed equally to the second one for 8 weeks. The clinical death of the animals was caused by overdosage of the solution of phenobarbital (1 mg/kg). The rats were weighed, the testicles and epididymis were eliminated, and pathohistological examinations were carried out.The average weight of the male rats in the control group was 1530+/-166.37mg, in the second group - 1520+/-164.62mg, and in the third group -1499+/-158.81 mg. Calculations of the relative quantity between the mass of the organs and the body weight were made and it was estimated that the testicles of the rats in the first group made up 0.496+/-0.399% of a body mass, in the second one -0.459+/-0.419%, and in the third one - 0.429+/-0.410%. The epididymis in the control group made up 0.189+/-0.332% of a body mass; in the second one - 0.1733+/-0.328%, and in the third one - 0.1723+/-0.198%. The histological structural changes were traced after 4 weeks of using the preparation, however they became more obvious after 8 weeks.Results of the study enabled to determine statistically significant reduction in the percentage of a testicle and the body mass, as well as changes in histological structures after 8 weeks of consuming extract of Echinacea purpurea." @default.
• W86352707 created "2016-06-24" @default.
• W86352707 creator A5029209945 @default.
• W86352707 creator A5034996898 @default.
• W86352707 creator A5037548108 @default.
• W86352707 date "2004-01-01" @default.
• W86352707 modified "2023-09-23" @default.
• W86352707 title "The effect of Echinacea purpurea extract on sexual glands of male rats." @default.
• W86352707 cites W1547137876 @default.
• W86352707 cites W1970886812 @default.
• W86352707 cites W2064583642 @default.
• W86352707 cites W2077251269 @default.
• W86352707 cites W2087013943 @default.
• W86352707 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15630349" @default.
• W86352707 hasPublicationYear "2004" @default.
• W86352707 type Work @default.
• W86352707 sameAs 86352707 @default.
• W86352707 citedByCount "1" @default.
• W86352707 countsByYear W863527072013 @default.
• W86352707 crossrefType "journal-article" @default.
• W86352707 hasAuthorship W86352707A5029209945 @default.
• W86352707 hasAuthorship W86352707A5034996898 @default.
• W86352707 hasAuthorship W86352707A5037548108 @default.
• W86352707 hasConcept C121608353 @default.
• W86352707 hasConcept C126322002 @default.
• W86352707 hasConcept C133507102 @default.
• W86352707 hasConcept C134018914 @default.
• W86352707 hasConcept C16685009 @default.
• W86352707 hasConcept C2776235491 @default.
• W86352707 hasConcept C2777562237 @default.
• W86352707 hasConcept C2779066085 @default.
• W86352707 hasConcept C2779279991 @default.
• W86352707 hasConcept C2781087480 @default.
• W86352707 hasConcept C2781254305 @default.
• W86352707 hasConcept C42407357 @default.
• W86352707 hasConcept C71315377 @default.
• W86352707 hasConcept C71924100 @default.
• W86352707 hasConceptScore W86352707C121608353 @default.
• W86352707 hasConceptScore W86352707C126322002 @default.
• W86352707 hasConceptScore W86352707C133507102 @default.
• W86352707 hasConceptScore W86352707C134018914 @default.
• W86352707 hasConceptScore W86352707C16685009 @default.
• W86352707 hasConceptScore W86352707C2776235491 @default.
• W86352707 hasConceptScore W86352707C2777562237 @default.
• W86352707 hasConceptScore W86352707C2779066085 @default.
• W86352707 hasConceptScore W86352707C2779279991 @default.
• W86352707 hasConceptScore W86352707C2781087480 @default.
• W86352707 hasConceptScore W86352707C2781254305 @default.
• W86352707 hasConceptScore W86352707C42407357 @default.
• W86352707 hasConceptScore W86352707C71315377 @default.
• W86352707 hasConceptScore W86352707C71924100 @default.
• W86352707 hasIssue "12" @default.
• W86352707 hasLocation W863527071 @default.
• W86352707 hasOpenAccess W86352707 @default.
• W86352707 hasPrimaryLocation W863527071 @default.
• W86352707 hasRelatedWork W130698877 @default.
• W86352707 hasRelatedWork W1982258064 @default.
• W86352707 hasRelatedWork W2027210979 @default.
• W86352707 hasRelatedWork W2041994514 @default.
• W86352707 hasRelatedWork W2047880909 @default.
• W86352707 hasRelatedWork W2153510880 @default.
• W86352707 hasRelatedWork W2394390748 @default.
• W86352707 hasRelatedWork W2473203491 @default.
• W86352707 hasRelatedWork W3119374407 @default.
• W86352707 hasRelatedWork W86352707 @default.
• W86352707 hasVolume "40" @default.
• W86352707 isParatext "false" @default.
• W86352707 isRetracted "false" @default.
• W86352707 magId "86352707" @default.
• W86352707 workType "article" @default.