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- W86353477 abstract "CHO cells grown adherent undergo a series of physiological and morphological changes when reaching cell to cell contact. The physiological parameters determined in this study included growth rate, RNA content, mitochondrial membrane potential and cell cycle distribution. When cells harvested at different time points during a surface limited batch culture were transferred into spinner flasks and cultivated in serumfree medium, the cells that were still metabolically active were better able to adapt to the serumfree environment than cells that had already switched their metabolism to maintenance. These results could be confirmed in fluidised bed fermentations with macroporous glasscarriers." @default.
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- W86353477 date "1992-01-01" @default.
- W86353477 modified "2023-09-27" @default.
- W86353477 title "ADAPTATION OF rCHO CELLS TO GROWTH IN SERUM FREE MEDIUM: A FLOW CYTOMETRIC STUDY" @default.
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- W86353477 doi "https://doi.org/10.1016/b978-0-7506-0421-5.50041-6" @default.
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