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• W86525370 abstract "To review the evolution and current status of probe ablative methods of minimally invasive nephron-sparing surgery (MINSS) for renal tumours. The English language literature of the past 10 yr was reviewed by using the National Library of Medicine database and the following keywords: chemoablation, cryoablation, high-intensity focused ultrasound, kidney, laser interstitial thermotherapy, microwave thermotherapy, nephron-sparing surgery, radiofrequency ablation, radiosurgery, renal, and tumour. Over 300 papers were identified, 50 of which were selected for this review on the basis of their contribution in advancing the field with regards to (1) evolution of concepts, (2) development and refinement of techniques, and (3) intermediate- and long-term clinical outcomes. Open partial nephrectomy is the reference standard for nephron-sparing surgery against which all MINSS techniques should be measured. Although the initial outcomes of cryoablation and radiofrequency ablation (RFA) are encouraging, long-term studies are necessary to confirm lasting efficacy. The optimal modality for tumour targeting, monitoring therapy, and follow-up remains to be determined. These ablative techniques should be reserved for carefully selected patients, the data should be prospectively accrued, and the long-term cancer cure rates should be compared with the reference standard. Promising long-term data are available for cryoablation. RFA is still considered developmental, and instances of incomplete cell kill, despite nonenhancement, are concerning. Other modalities are still experimental." @default.
• W86525370 created "2016-06-24" @default.
• W86525370 creator A5006744077 @default.
• W86525370 creator A5047742848 @default.
• W86525370 date "2007-02-01" @default.
• W86525370 modified "2023-10-18" @default.
• W86525370 title "Minimally Invasive Nephron-Sparing Surgery (MINSS) for Renal Tumours" @default.
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• W86525370 doi "https://doi.org/10.1016/j.eururo.2006.10.033" @default.
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• W86525370 hasPublicationYear "2007" @default.
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