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- W86644718 abstract "This chapter discusses the anatomy and physiology of the human thalamic and cortical structures that may mediate the sensation of pain. The human thalamic and cortical structures are the sensory discriminative and the motivational-affective aspect of pain. Studies in humans have demonstrated the involvement of both the lateral and medial thalamus in pain processing. In the lateral thalamus, cells responsive to painful stimuli are located in the core area and in the postero-inferior area. Stimulation in the postero-inferior area or at the posterior aspect of the core can evoke pain or visceral pain suggesting the involvement of this area in the mechanism of somatic and visceral pain. Abnormalities in the lateral thalamus in patients with chronic pain point to the involvement of this area in chronic pain in humans. A reorganization of modalities occurs in patients with chronic pain so that the number of sites where thermal sensations are normally evoked by thalamic stimulation is decreased by an amount equal to the increase in the number of sites where pain is evoked." @default.
- W86644718 created "2016-06-24" @default.
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- W86644718 date "2004-01-01" @default.
- W86644718 modified "2023-10-11" @default.
- W86644718 title "Chapter 6 The role of the thalamus in pain" @default.
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- W86644718 doi "https://doi.org/10.1016/s1567-424x(09)70342-3" @default.
- W86644718 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16106605" @default.
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