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- W869513510 abstract "A novel artificial site specific cleavage reagent, with peptide nucleic acid (PNA) as sequence-recognizing moiety and cerium (Ⅳ) ions as scissors for cleaving target DNA, was synthesized. Subsequently, it was employed in the cleavage of target 26-mer single-stranded DNA (ssDNA), which has 10-mer sequence complementary with PNA recognizer in the hybrids,under physiological conditions. Reversed-phase high-performance liquid chromatogram (RPHPLC) experiments indicated that the artificial site specific cleavage reagent could cleave the target DNA specifically." @default.
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- W869513510 date "2005-01-01" @default.
- W869513510 modified "2023-09-23" @default.
- W869513510 title "Sequence-specific Hydrolysis of Single-stranded DNA by PNA-Cerium （IV） Adduct" @default.
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