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- W870890259 abstract "目的探讨在大肠癌中EGFR、c-erbB-2、CD44v6和p53基因蛋白联合表达与病理特征的关系，以及在各临床阶段的表达差异。方法对63例存档大肠癌石蜡组织标本进行重新切片，分别采用EGFR、c-erbB-2、CD44v6和p53四种单克隆抗体进行免疫组化染色(SABC法)。染色结果与大肠癌分化程度、浸润深度及临床分期(Dukes)进行比较。结果EGFR、c-erbB-2、CD44v6和p53联合阳性表达与大肠癌肿瘤大小、组织分级、浸润深度均无显著相关；而随着临床分期的进展，阳性表达的基因数目逐渐增多，二者之间具有显著线性相关趋势。结论联合检测EGFR、c-erbB-2、CD44v6和p53对准确判断大肠癌浸润转移有所帮助。" @default.
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- W870890259 date "2001-05-05" @default.
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- W870890259 title "Relation between Clinicopathological Stage and the Co-expression of EGFR, c-erbB-2, CD44v6 and p53 in Colorectal Cancer" @default.
- W870890259 doi "https://doi.org/10.3971/j.issn.1000-8578.2155" @default.
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