Matches in SemOpenAlex for { <https://semopenalex.org/work/W87265424> ?p ?o ?g. }
- W87265424 endingPage "307" @default.
- W87265424 startingPage "251" @default.
- W87265424 abstract "Natural products are recognized as a rich source of bioactive compounds for modern medicine, particularly those for the treatment of cancer. Since natural products are metabolites of living organisms, they have a tendency to bind or interact with biomolecules in living cells such as proteins, enzymes, DNA, RNA, and receptors, some of which are drug targets. This special property makes natural compounds to be the ideal sources for the drug development. Cancer is a serious health threat, and it is known as the leading cause of death worldwide. Recent anticancer drug development is heavily based on drug targets, that is, proteins, enzymes, and receptors, and this mechanism-based drug discovery would significantly shorten the drug development process. This chapter covers the recent development of anticancer drugs, which are from natural products or inspired by natural products. Recently, several new anticancer drugs and potential anticancer leads have been discovered through the rational drug design on different drug targets. This chapter highlights natural anticancer drugs and leads, as well as derivatives of natural products, which are discovered through the most recently employed anticancer drug targets, for example, tubulin/microtubule interaction, tyrosine kinases, cyclin-dependent kinases, heat shock protein 90, Hedgehog signaling pathway, and histone deacetylase." @default.
- W87265424 created "2016-06-24" @default.
- W87265424 creator A5002924322 @default.
- W87265424 date "2015-01-01" @default.
- W87265424 modified "2023-10-01" @default.
- W87265424 title "Anticancer Drugs and Potential Anticancer Leads Inspired by Natural Products" @default.
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