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- W8726649 abstract "Toxoplasma gondii is an apicomplexan obligate intracellular parasite and the most extensively studied of the tissue encysting coccidia. It has been estimated that one third of the world population has been infected (Dubey 2008e, Su 2003, Tenter 2000). In most human adults it does not cause serious illness, however, blindness and mental retardation can be caused in congenitally infected children and severe diseases in those with compromised immunity (Luft 1992, Montoya 2004). A recent study indicated that infection with T. gondii is also associated with abdominal hernia (Alvarado 2011) and could increase the risk of brain cancer because it is a long-lived parasite that encysts in the brain, where it provokes inflammation and inhibits apoptosis (Thomas 2011). T. gondii has been differentiated in three major groups, type I, II and III (Darde 2003, Howe 1995, 1997, Sibley 1992). In pigeons, different prevalences have been described, ranging from 4,6% to 100% (Cotteleer 1978, Kirkpatrick 1990, Mushi 2000, Tsai 2006, Waap 2008, Salant 2009, Yan 2011). In Portugal there is only a preliminary study in pigeons typing developed by our work group (Waap 2008). The microsatellite typing revealed that 75% of strains belonged to type II, 16,7% were type III and 8,3% was type I (Waap 2008). This work is part of a global study which aim is to help the understanding of the portuguese reality that concerns Toxoplasma gondii typing and virulence strains. INTRODUCTION" @default.
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- W8726649 date "2012-04-01" @default.
- W8726649 modified "2023-09-27" @default.
- W8726649 title "Genetic and virulence characterization of Toxoplasma gondii strains isolated from pigeons in Lisbon region" @default.
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