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- W87309740 endingPage "249" @default.
- W87309740 startingPage "173" @default.
- W87309740 abstract "The principal elements of cytoplasm structure and biological membranes are the phospholipids containing unsaturated fatty acid chains. The protein constituents, amino acids, nucleotides, carbohydrates, or coenzymes do not show such lability as is typical of unsaturated fatty acids in an oxygen-rich atmosphere. Biological membranes are filled with active catalysts of oxidation of fatty acids by oxygen with peroxide formation. The consequences of oxidation of a small portion of unsaturated fatty acids in the phospholipid bilayer are dramatic: deterioration of barrier and matrix function of the lipid bilayer, enzyme inactivation, and toxic effects on cell division. The formation of membranes in primary cells proceeded in reduced atmosphere, and later the cells developed specialized systems to protect their membrane substance against oxidation by free oxygen. The process of lipid peroxidation might be specific in many respects to each particular membrane formation in given types of cells, though there are some general features of this phenomenon intrinsic to any membrane structure in any cell." @default.
- W87309740 created "2016-06-24" @default.
- W87309740 creator A5001437608 @default.
- W87309740 creator A5018974997 @default.
- W87309740 creator A5039657982 @default.
- W87309740 creator A5071701554 @default.
- W87309740 date "1980-01-01" @default.
- W87309740 modified "2023-10-01" @default.
- W87309740 title "Lipid Peroxidation in Mitochondrial Membrane" @default.
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