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- W874922 endingPage "46" @default.
- W874922 startingPage "1" @default.
- W874922 abstract "Neglected tropical diseases (NTDs), caused by a host of pathogens including helminthes, protozoa, bacteria, and viruses, remain a difficult and challenging area for drug discovery, being limited by meager resources and funding, challenged by gaps in knowledge of pathogen biology and drug targets, and faced with limitations specific to the developing world, including stringent cost of good constraints, the lack of robust infrastructure to effectively deliver and administer drug therapy, and socioeconomic considerations in disease endemic areas. This chapter will endeavor to provide a general overview of scientific approaches for NTDs, and review some of the current challenges and advancements in diseases of the developing world (DDW) drug discovery, as well as discuss the interplay between international networks of organizations, foundations, and public and private partners involved in neglected disease drug discovery. This chapter will also review general aspects and considerations common to many or all of these diseases, including burden of disease, coinfections, pathogenicity, drug resistance, drug combination therapy, and mass drug administration programs. This chapter will briefly address disease treatment on a general level, including the treatment of coinfections and care of special groups of patients, such as children and pregnant women." @default.
- W874922 created "2016-06-24" @default.
- W874922 creator A5046402277 @default.
- W874922 date "2011-01-01" @default.
- W874922 modified "2023-09-23" @default.
- W874922 title "Overview of Neglected Tropical Diseases" @default.
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