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- W876329537 abstract "As a selective antagonist, tamsulosin has been used clinically for urinary obstructed patients with benign prostatic hyperplasia. The single and multi-layered pellets containing tamsulosin hydrochloride were prepared in an effort to control the drug release, avoiding dose-dependent side effects of tamsulosin hydrochloride upon oral administration. The drug release from multi-layered pellets was substantially controlled, compared with single layered pellets. The drug release from coated pellets with single or multi layer was affected by the nature of coating agent, the percentage of coating level and the presence of hydrophilic material in coating layer. In conclusion, the controlled release oral delivery system using multi-layered pellet is very useful for tamsulosin hydrochloride, resulting in improvement of patient compliance and therapeutic drug levels for a longer period of time." @default.
- W876329537 created "2016-06-24" @default.
- W876329537 date "2005-12-20" @default.
- W876329537 modified "2023-09-25" @default.
- W876329537 title "Preparation and Dissolution Profiles of Controled Release Formulations Containing Tamsulosin Hydrochloride" @default.
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- W876329537 doi "https://doi.org/10.4333/kps.2005.35.6.445" @default.
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