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• W876483149 startingPage "10" @default.
• W876483149 abstract "Glycoprotein (GP) IIb/IIIa inhibitors block platelet aggregation, reducing thrombotic events in acute coronary syndrome. They are most often utilized in patients who likely have an intracoronary thrombus. Tirofiban, eptifibatide, and abciximab are the three GP IIb/IIIa inhibitors approved for use in the United States. Each agent has unique pharmacological properties. They all have a rapid onset and are most often utilized in conjunction with heparin. Tirofiban, in particular, fell out of favor due to inferior dosing with its original Food and Drug Administration (FDA) approved indication, but has re-emerged in the market with a high-dose bolus regimen that is considered equally as effective as the FDA approved dosing regimens of other GP IIb/IIIa inhibitors. This review looks at pharmacological properties of all three agents, significant clinical trials associated with their use, and their place in current guidelines." @default.
• W876483149 created "2016-06-24" @default.
• W876483149 creator A5022938121 @default.
• W876483149 creator A5044216299 @default.
• W876483149 creator A5064869493 @default.
• W876483149 date "2016-03-01" @default.
• W876483149 modified "2023-10-16" @default.
• W876483149 title "Glycoprotein IIb/IIIa inhibitors: The resurgence of tirofiban" @default.
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• W876483149 doi "https://doi.org/10.1016/j.vph.2015.07.008" @default.
• W876483149 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26187354" @default.
• W876483149 hasPublicationYear "2016" @default.
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