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- W87672218 abstract "566 Objectives Cardiac tumors are rare. Non-invasive determination of the malignancy of newly diagnosed cardiac tumors is of major merit. To date there are few cases reported using 18F-FDG-PET/CT as a diagnostic method in the initial workup. Morphological imaging offers data about location and contrast enhancement and helps to distinguish benign from malignant cardiac tumors in some cases, but there is no non-invasive quantitative metabolic imaging modality differentiating malignancy of cardiac tumors with high accuracy. The aim of this study was to evaluate the incremental diagnostic value of 18F-FDG uptake in this clinical situation. Methods Data from 21 patients (10 male, 11 female; mean age ± standard deviation: 58 ± 17 years) with newly diagnosed cardiac tumors undergoing FDG-PET/CT scans (whole body imaging with low dose CT) as part of the initial assessment were included in the analysis. The maximum standard uptake values (SUVmax) were measured in all tumors and compared to the final diagnosis obtained by histology. The patients were divided into 3 groups: 1) benign cardiac tumors (n=5), 2) malignant primary cardiac tumors (n=7), and 3) malignant secondary cardiac tumors (n=9). The FDG uptake was compared between groups. Results The mean maximum standard uptake values of the tumors (SUVmax) were 2.7 (Range: 1.6 - 4.0), 7.2 (5.3 - 10.7) and 10.8 (3.4 - 16.7) in group 1-3, respectively. The mean SUVmax was significantly higher in primary and secondary malignant cardiac tumors than in benign cardiac tumors (P Conclusions FDG-PET/CT shows promising results in the determination of malignancy and initial staging. FDG-PET/CT may gain importance in the therapeutic management of patients with malignant cardiac tumors" @default.
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- W87672218 date "2010-05-01" @default.
- W87672218 modified "2023-10-08" @default.
- W87672218 title "FDG-PET/CT in patients with cardiac tumors" @default.
- W87672218 hasPublicationYear "2010" @default.
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