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• W87991605 abstract "Recurrent spontaneous abortion (RSA) is one of the most common health complications with a strong genetic component. Several genetic disorders were identified as etiological factors of hereditary X linked RSA. However, more genetic factors remain to be identified.In this study we performed linkage analysis on a large X linked RSA pedigree to find a novel susceptibility locus for RSA.A linkage scan using 11 microsatellites was performed in 27 members of a large pedigree of hereditary X-linked RSA. Two point parametric Linkage was performed using Superlink v 1.6 program.Evidence of linkage was observed to markers at Xq23, DXS7133 and at Xq22.1 DXS101, with LOD score of 3.12 and 1.60, respectively.Identified locus in this study may carry a responsible gene in RSA. Narrowing down of this region may leads to identification of this gene. This article extracted from M.Sc. thesis. (Sahar Shekouhi)." @default.
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• W87991605 date "2013-08-01" @default.
• W87991605 modified "2023-09-26" @default.
• W87991605 title "Identification of Xq22.1-23 as a region linked with hereditary recurrent spontaneous abortion in a family." @default.
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• W87991605 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3941371" @default.
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